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2000
Volume 10, Issue 2
  • ISSN: 1573-4013
  • E-ISSN: 2212-3881

Abstract

Introduction

Emerging evidence supports that increased consumption of dry beans ( L.) reduces both the incidence and recurrence of adenomatous polyps or precancerous growths. Navy beans have been studied for dietary colorectal cancer (CRC) chemoprevention in animal models. Our main objectives were to assess the feasibility of increased navy bean consumption in adults with and without history of CRC and to achieve intake amounts associated with chemoprevention.

Methods

Seven meals and six snacks were developed for both the absence and inclusion of cooked navy bean powder (35grams/day). Sixteen healthy adults (7 non-cancer and 9 CRC survivors) completed the placebo-controlled, randomized, single-blinded dietary intervention trial. Participants consumed one study-provided meal and snack daily for 28 days, which accounted for approximately one-third of their total recommended caloric intake (meals = 202-483 kcal and snacks = 194-401 kcal). Participants also recorded three-day dietary food logs each week.

Results

The addition of 35g of cooked navy bean powder (NBP) into foods provided 5-8% daily caloric intake. The compliance to the meal and snack intervention ranged from 89-100%. Non-cancer participants in the NBP group had a significant decrease in total caloric intake after week 4 (p≤0.0001). CRC survivors in the NBP group significantly increased total fiber intake by week 4 (p≤0.0001).

Conclusions

NBP are feasible to include in meals for increased total fiber intake and for consuming the amount that is associated with CRC chemoprevention outcomes. These findings warrant further evaluation of NBP consumption in clinical nutrition trials for CRC control and prevention.

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2025-09-27
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References

  1. American Cancer Society. Colorectal cancer facts & figures 2011-2013.AtlantaAmerican Cancer Society,2011
    [Google Scholar]
  2. World Cancer Research Fund / American Institute for Cancer Research. Food, nutrition, physical activity, and the prevention of cancer: a global perspective.Washington DCAICR,2007
    [Google Scholar]
  3. PereraP.S. ThompsonR.L. WisemanM.J. Recent evidence for colorectal cancer prevention through healthy food, nutrition, and physical activity: implications for recommendations.Curr. Nutr. Rep.201214454
    [Google Scholar]
  4. XuB.J. ChangS.K.C. Comparative study on antiproliferation properties and cellular antioxidant activities of commonly consumed food legumes against nine human cancer cell lines.Food Chem.201213412871296
    [Google Scholar]
  5. BobeG. BarrettK.G. Mentor-MarcelR.A. Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced Ob/Ob mice.Nutr. Cancer200860373381
    [Google Scholar]
  6. LanzaE. HartmanT.J. AlbertP.S. High dry bean intake and reduced risk of advanced colorectal adenoma recurrence among participants in the polyp prevention trial.J. Nutr.200613618961903
    [Google Scholar]
  7. HangenL. BenninkM.R. Consumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in rats.Nutr. Cancer2002446065
    [Google Scholar]
  8. GeilP.B. AndersonJ.W. Nutrition and health implications of dry beans - a review.J. Am. Coll. Nutr.199413549558
    [Google Scholar]
  9. HughesJ.S. GanthavornC. Wilson-SandersS. Dry beans inhibit azoxymethane-induced colon carcinogenesis in F344 rats.J. Nutr.199712723282333
    [Google Scholar]
  10. HartmanT.J. AlbertP.S. ZhangZ. Consumption of a legume-enriched, low-glycemic index diet is associated with biomarkers of insulin resistance and inflammation among men at risk for colorectal cancer.J. Nutr.20101406067
    [Google Scholar]
  11. Mentor-MarcelR.A. BobeG. BarrettK.G. Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in Ob/Ob mice.Cancer Prev. Res.200926069
    [Google Scholar]
  12. ParkY. SubarA.F. HollenbeckA. Dietary fiber intake and mortality in the NIH-AARP diet and health study.Arch. Intern. Med.201117110611068
    [Google Scholar]
  13. SinghP.N. FraserG.E. Dietary risk factors for colon cancer in a low-risk population.Am. J. Epidemiol.1998148761774
    [Google Scholar]
  14. MichelsK.B. GiovannucciE. ChanA.T. Fruit and vegetable consumption and colorectal adenomas in the Nurses’ Health Study.Cancer Res.20066639423953
    [Google Scholar]
  15. Smiciklas-WrightH. MitchellD.C. MickleS.J. Foods commonly eaten in the United States: Quantities consumed per eating occasion and in a day, 1994-96. U.S. Department of Agriculture NFS Report No. 96-5, 2002;Available at: www.ars.usda.gov/SP2UserFiles/Place/12355000/pdf/Portion.pdf
  16. MitchellD.C. LawrenceF.R. HartmanT.J. Consumption of dry beans, peas, and lentils could improve diet quality in the US population.J. Am. Diet. Assoc.2009109909913
    [Google Scholar]
  17. LucierG. LinB.H. AllshouseJ. Factors affecting dry bean consumption in the United States (2000). US Department of Agriculture. Vegetables and Specialties. Economic Research Service website. http://webarchives.cdlib.org/sw1bc3ts3z/ http://ers.usda.gov/Briefing/DryBeans/PDFs/DryBeanConsumption.pdf. Accessed Septmber 2012.
  18. Archer Daniels Midland Company: VegeFull™ Cooked Ground Bean Ingredients (2011).Available at: www.adm.com/vegefull. Accessed September 2012.
  19. BerriosJ. Extrusion cooking of legumes: Dry bean flours.Encyclopedia of Agricultural, Food and Biological Engineering200618
    [Google Scholar]
  20. BerriosJ.D. WoodD.F. WhitehandL. Sodium bicarbonate and the microstructure, expansion and color of extruded black beans.J. Food Process. Preserv.200428321335
    [Google Scholar]
  21. AntonA.A. RossK.A. LukowO.M. Influence of added bean flour (Phaseolus vulgaris L.) on some physical and nutritional properties of wheat flour tortillas.Food Chem.20081093341
    [Google Scholar]
  22. AntonA.A. FulcherR.G. ArntfieldS.D. Physical and nutritional impact of fortification of corn starch-based extruded snacks with common bean (Phaseolus vulgaris L.) flour: Effects of bean addition and extrusion cooking.Food Chem.2009113989996
    [Google Scholar]
  23. SiddiqM. RaviR. HarteJ.B. Physical and functional characteristics of selected dry bean (Phaseolus vulgaris L.) flours.LWTFoodSci Technol201043232237
    [Google Scholar]
  24. ThompsonM.D. ThompsonH.J. BrickM.A. Mechanisms associated with dose-dependent inhibition of rat mammary carcinogenesis by dry bean (Phaseolus vulgaris, L.).J. Nutr.200813820912097
    [Google Scholar]
  25. ZhangZ. LanzaE. Kris-EthertonP.M. A high legume low glycemic index diet improves serum lipid profiles in men.Lipids201045765775
    [Google Scholar]
  26. HermsdorffH.H. ZuletM.A. AbeteI. A legume-based hypocaloric diet reduces proinflammatory status and improves metabolic features in overweight/obese subjects.Eur. J. Nutr.2011506169
    [Google Scholar]
  27. ZhuZ.J. JiangW.Q. ThompsonH.J. Edible dry bean consumption (Phaseolus vulgaris L.) modulates cardiovascular risk factors and diet-induced obesity in rats and mice.Brit J. Nutr.2012108S66S73
    [Google Scholar]
  28. HayatI. AhmadA. MasudT. Nutritional and health perspectives of beans (Phaseolus vulgaris L.): An overview.Crit. Rev. Food Sci.201454580592
    [Google Scholar]
  29. Dietary Reference Intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids. [database on the Internet]. Institute of Medicine, Food and Nutrition Board Web site.Available at: http://www.iom.edu/Reports/2002/Dietary-Reference-Intakes-for-Energy-Carbohydrate-Fiber-Fat-Fatty-Acids-Cholesterol-Protein-and-Amino-Acids.aspx. Accessed October 2012.
  30. KingD.E. MainousA.G. Trends in dietary fiber intake in the United States, 1999-2008.J. Acad. Nutr. Diet.2012112642648
    [Google Scholar]
  31. BroughtonW.J. HernandezG. BlairM. Beans (Phaseolus spp.) - model food legumes.Plant Soil200325255128
    [Google Scholar]
  32. WinhamD.M. HutchinsA.M. Perceptions of flatulence from bean consumption among adults in 3 feeding studies.Nutr. J.201110128
    [Google Scholar]
  33. RebelloC.J. GreenwayF.L. FinleyJ.W. A review of the nutritional value of legumes and their effects on obesity and its related co-morbidities.Obes. Rev.201410.1111/obr.12144
    [Google Scholar]
  34. KabagambeE.K. BaylinA. Ruiz-NarvarezE. Decreased consumption of dried mature beans is positively associated with urbanization and nonfatal acute myocardial infarction.J. Nutr.200513517701775
    [Google Scholar]
  35. Darmadi-BlackberryI. WahlqvistM.L. Kouris-BlazosA. Legumes: the most important dietary predictor of survival in older people of different ethnicities.Asia Pac. J. Clin. Nutr.200413217220
    [Google Scholar]
  36. ChangW.C. WahlqvistM.L. ChangH.Y. A bean-free diet increases the risk of all-cause mortality among Taiwanese women: the role of the metabolic syndrome.Public Health Nutr.201215663672
    [Google Scholar]
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