f The Therapeutic Promise of Isorhamnetin in Breaking the Obesity-Cancer Link

References

1. AvgerinosK.I. SpyrouN. MantzorosC.S. DalamagaM. Obesity and cancer risk: Emerging biological mechanisms and perspectives.Metabolism20199212113510.1016/j.metabol.2018.11.001 30445141
   [Google Scholar]
2. BoothA. MagnusonA. FoutsJ. FosterM. Adipose tissue, obesity and adipokines: Role in cancer promotion.Horm. Mol. Biol. Clin. Investig.2015211577410.1515/hmbci‑2014‑0037 25781552
   [Google Scholar]
3. KumarM. HussainM.S. SonuR.S. An overview of treatment modalities and management aspects for obesity.Curr. Nutr. Food Sci.202319210511310.2174/1573401318666220527124759
   [Google Scholar]
4. ParkJ. MorleyT.S. KimM. CleggD.J. SchererP.E. Obesity and cancer—mechanisms underlying tumour progression and recurrence.Nat. Rev. Endocrinol.201410845546510.1038/nrendo.2014.94 24935119
   [Google Scholar]
5. BahlG. PathakY. HussainM.S. GuptaY. SaraswatN. Navigating Sheehan syndrome’s silent onset: A case report.J. Clin. Transl. Endocrinol. Case Rep.20243210016810.1016/j.jecr.2024.100168
   [Google Scholar]
6. GongG. GuanY.Y. ZhangZ.L. Isorhamnetin: A review of pharmacological effects.Biomed. Pharmacother.202012811030110.1016/j.biopha.2020.110301 32502837
   [Google Scholar]
7. HussainM.S. GuptaG. GoyalA. From nature to therapy: Luteolin’s potential as an immune system modulator in inflammatory disorders.J. Biochem. Mol. Toxicol.20233711e2348210.1002/jbt.23482 37530602
   [Google Scholar]
8. González-ArceoM. Gomez-LopezI. Carr-UgarteH. Anti-obesity effects of isorhamnetin and isorhamnetin conjugates.Int. J. Mol. Sci.202224129910.3390/ijms24010299 36613743
   [Google Scholar]
9. Shaik Mohamed SayedU.F. MoshawihS. GohH.P. Natural products as novel anti-obesity agents: Insights into mechanisms of action and potential for therapeutic management.Front. Pharmacol.202314118293710.3389/fphar.2023.1182937 37408757
   [Google Scholar]
10. RussoC. MaugeriA. MusumeciL. De SarroG. CirmiS. NavarraM. Inflammation and obesity: The pharmacological role of flavonoids in the zebrafish model.Int. J. Mol. Sci.2023243289910.3390/ijms24032899 36769222
    [Google Scholar]
11. BarrecaM.M. AlessandroR. CorradoC. Effects of flavonoids on cancer, cardiovascular and neurodegenerative diseases: Role of NF-κB signaling pathway.Int. J. Mol. Sci.20232411923610.3390/ijms24119236 37298188
    [Google Scholar]
12. TufailM. WuC. HussainM.S. Dietary, addictive and habitual factors, and risk of colorectal cancer.Nutrition202412011233410.1016/j.nut.2023.112334 38271761
    [Google Scholar]
13. Jamali-RaeufyN. BaluchnejadmojaradT. RoghaniM. KeimasiS. GoudarziM. Isorhamnetin exerts neuroprotective effects in STZ-induced diabetic rats via attenuation of oxidative stress, inflammation and apoptosis.J. Chem. Neuroanat.201910210170910.1016/j.jchemneu.2019.101709 31698018
    [Google Scholar]
14. ChoiY.H. Isorhamnetin induces ROS-dependent cycle arrest at G2/M phase and apoptosis in human hepatocarcinoma Hep3B cells.Gen. Physiol. Biophys.201938647348410.4149/gpb_2019038 31588915
    [Google Scholar]
15. LeeM. KimJ. ChoiJ. Anti-obesity effect in high-fat-diet-induced obese C57BL/6 mice: Study of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris.Exp. Ther. Med.20191732185219310.3892/etm.2019.7191 30867704
    [Google Scholar]
16. SchulzH.U. SchürerM. BässlerD. WeiserD. Investigation of pharmacokinetic data of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin revealed from single and multiple oral dose studies with a hypericum extract containing tablet in healthy male volunteers.Arzneimittelforschung20055510561568 16294501
    [Google Scholar]
17. SchulzH.U. SchürerM. BässlerD. WeiserD. Investigation of the bioavailability of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin following single and multiple oral dosing of a hypericum extract containing tablet.Arzneimittelforschung20055511522 15727160
    [Google Scholar]
18. LiG. ZengX. XieY. Pharmacokinetic properties of isorhamnetin, kaempferol and quercetin after oral gavage of total flavones of Hippophae rhamnoides L. in rats using a UPLC–MS method.Fitoterapia201283118219110.1016/j.fitote.2011.10.012 22056665
    [Google Scholar]
19. GalatiG. O’BrienP.J. Potential toxicity of flavonoids and other dietary phenolics: Significance for their chemopreventive and anticancer properties.Free Radic. Biol. Med.200437328730310.1016/j.freeradbiomed.2004.04.034 15223063
    [Google Scholar]
20. MoonY.J. WangX. MorrisM.E. Dietary flavonoids: Effects on xenobiotic and carcinogen metabolism.Toxicol. In Vitro200620218721010.1016/j.tiv.2005.06.048 16289744
    [Google Scholar]