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2000
Volume 21, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603

Abstract

Introduction:

This article presents a case of a patient with a broad ligament perivascular epithelioid cell tumor (PEComa), focusing on the analysis of its imaging features in CT and MRI to enhance understanding and awareness of this rare tumor.

Case Presentation:

This article reports a case of a 27-year-old married woman who was found to have a pelvic mass two years ago. After detailed examination at our hospital, imaging studies, including enhanced CT and MRI, revealed a cystic-solid lesion in the left adnexal area, with preoperative considerations of ovarian cystadenoma or uterine leiomyoma. She was referred to a specialized obstetrics and gynecology hospital for surgery, and the postoperative pathology was diagnosed as PEComa. She has been undergoing regular follow-up at our hospital post-surgery. One year after the operation, her laboratory tests showed no significant abnormalities, and imaging studies did not reveal any signs of metastasis.

Conclusion:

Uterine broad ligament PEComa is a rare tumor, and accurate imaging features and classification criteria can aid in improving preoperative diagnosis. A deeper understanding of the clinical and imaging characteristics of this rare disease is significant for enhancing diagnostic accuracy and treatment outcomes.

This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
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2025-10-15
2025-12-10
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References

  1. MusellaA. De FeliceF. KyriacouA.K. BarlettaF. Di MatteoF.M. MarchettiC. IzzoL. MontiM. Benedetti PaniciP. RedlerA. D’AndreaV. Perivascular epithelioid cell neoplasm (PEComa) of the uterus: A systematic review.Int J Surg2015191510.1016/j.ijsu.2015.05.00225981307
    [Google Scholar]
  2. BonettiF. PeaM. MartignoniG. ZamboniG. PEC and sugar.Am J Surg Pathol199216330730810.1097/00000478‑199203000‑000131599021
    [Google Scholar]
  3. MartignoniG. PeaM. ZampiniC. BrunelliM. SegalaD. ZamboniG. BonettiF. PEComas of the kidney and of the genitourinary tract.Semin Diagn Pathol201532214015910.1053/j.semdp.2015.02.00625804448
    [Google Scholar]
  4. MartinsI.V. ProencS. Perivascular epithelioid cell neoplasm (PEComa) of the female genital tract: A systematic review.Clin Invest Ginecol Obstet2024514
    [Google Scholar]
  5. ArganiP. GrossJ.M. BarabanE. RooperL.M. ChenS. LinM.T. GockeC. AgaimyA. LotanT. SuurmeijerA.J.H. AntonescuC.R. TFE3-rearranged PEComa/PEComa-like neoplasms.Am J Surg Pathol202448777778910.1097/PAS.000000000000221838597260
    [Google Scholar]
  6. FolpeA.L. MentzelT. LehrH.A. FisherC. BalzerB.L. WeissS.W. Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: A clinicopathologic study of 26 cases and review of the literature.Am J Surg Pathol200529121558157510.1097/01.pas.0000173232.22117.3716327428
    [Google Scholar]
  7. FinkD. MarsdenD.E. EdwardsL. CamarisC. HackerN.F. Malignant perivascular epithelioid cell tumor (PEComa) arising in the broad ligament.Int J Gynecol Cancer20041451036103910.1136/ijgc‑00009577‑200409000‑0004515361222
    [Google Scholar]
  8. ArganiP. WobkerS.E. GrossJ.M. MatosoA. FletcherC.D.M. AntonescuC.R. PEComa-like neoplasms characterized by ASPSCR1-TFE3 fusion.Am J Surg Pathol20224681153115910.1097/PAS.000000000000189435848761
    [Google Scholar]
  9. YanS. LuJ.J. ChenL. CaiW.H. WuJ.Z. Hepatic perivascular epithelioid cell tumors: The importance of preoperative diagnosis.World J Gastroenterol202430131926193310.3748/wjg.v30.i13.192638659487
    [Google Scholar]
  10. AmanteM.F. Hepatic perivascular epithelioid cell tumors: Benign, malignant, and uncertain malignant potential.World J Gastroenterol202430182374237810.3748/wjg.v30.i18.237438764772
    [Google Scholar]
  11. BennettJ.A. OlivaE. Perivascular epithelioid cell tumors ( PEComa ) of the gynecologic tract.Genes Chromosomes Cancer202160316817910.1002/gcc.2290833099813
    [Google Scholar]
  12. GuJ. WangW. WangS. A retrospective case study of 13 uterine perivascular epithelioid cell neoplasm (PEComa) patients.OncoTargets Ther2021141783179010.2147/OTT.S30052333727828
    [Google Scholar]
  13. WangR. LuoH. CaoW. Clinical and ultrasound features of uterine perivascular epithelioid cell tumors: Case series and literature review.Ultrasound Obstet Gynecol202464568769510.1002/uog.2911639395194
    [Google Scholar]
  14. ShwayderJ. SakhelK. Imaging for uterine myomas and adenomyosis.J Minim Invasive Gynecol201421336237610.1016/j.jmig.2013.11.01124316138
    [Google Scholar]
  15. LiuX. LiuJ. ChenL. YangC. HuY. LiuY. Giant ovarian solid and cystic masses mixed with three types of tumors: A rare case report and literature review.Heliyon20241015e3507510.1016/j.heliyon.2024.e3507539161819
    [Google Scholar]
  16. GarzonS. CaliòA. FerrariF.A. IannicelloC.Q. ZorzatoP.C. BoscoM. PiazzolaE. MartignoniG. LaganàA.S. MarianiA. UccellaS. Uterine perivascular epithelioid cell tumors (PEComa) and the accuracy of proposed classification systems in predicting the malignant versus non-malignant behavior.Gynecol Oncol2024188354310.1016/j.ygyno.2024.06.00738905754
    [Google Scholar]
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