Current Medical Imaging - Online First

Primary cardiac tumors are rare. Most primary cardiac tumors are benign, with approximately 10.83% being malignant. We present a rare case of Primary Cardiac Angiosarcoma (PCA) with multiple metastases diagnosed using multimodality imaging, to enhance the understanding of PCA among clinicians and radiologists.

A 29-year-old woman presented to our hospital with a 2-day history of chest tightness, chest pain, palpitations, and dyspnea after physical activity. Ultrasonography and Computed Tomography (CT) of the heart revealed a mass in the right atrium. Cardiac magnetic resonance imaging suggested either a large cardiac lymphoma or angiosarcoma. The histopathological diagnosis confirmed a cardiac angiosarcoma. Positron Emission Tomography-Computed Tomography (PET/CT) revealed intense 18F-fluorodeoxyglucose (18F-FDG) uptake in the right side of the heart, with a maximum standardized uptake value of 10.9. Three months later, the patient was re-examined using abdominal CT, echocardiography, and PET/CT. PET/CT revealed increased 18F-FDG uptake which had become more extensive, with multifocal metastatic nodules in both the lungs and mediastinum. The patient was lost to follow-up after being discharged on May 1, 2022.

The combined evaluation using multimodality imaging plays a vital role in determining the precise size and localization of the PCA, detecting distant metastases, and assessing patient prognosis.

The objective of this study was to summarize the findings of children’s intracranial congenital or developmental malformations found during imaging procedures in the Tibetan plateau.

We retrospectively reviewed the imaging data of the suspected patients who presented with the central nervous system (CNS) malformations and were enrolled either through the clinic or after ultrasound examinations between June 2019 and June 2023 in our institution. All imaging data were interpreted by two experienced radiologists through consensus reading.

In this study, we recruited 36 patients, including two neonates, 17 infants and 17 children. Seven cases underwent an MRI examination, while the others had a CT scan. Polygyria and pachygyria malformation were the most common type of congenital neurological malformations (7 cases, 31.8%), followed by cystic changes of the cerebral parenchyma (3 cases, 13.6%). Cerebral atrophy was the most common type of secondary CNS abnormality(8 cases, 57.1%), followed by communicative hydrocephalus (3 cases, 21.4%). Five patients in the congenital group and 4 patients in the secondary group had complex malformations. In the current study group, there were 8 deaths, 12 cases with neurological sequelae, 1 case with normal development, and 15 cases lost to follow-up. There were no significant differences between the primary and secondary CNS groups in terms of the outcome for both the infants and children groups.

CNS malformations in the Tibetan Plateau are associated with high mortality and morbidity rates. Better utilization of imaging modalities could help design tailored treatments as early as possible.

Colon diseases are major global health issues that often require early detection and correct diagnosis to be effectively treated. Deep learning approaches and recent developments in medical imaging have demonstrated promise in increasing diagnostic accuracy.

This work suggests that a Convolutional Neural Network (CNN) model paired with other models can detect different gastrointestinal (GI) abnormalities or diseases from endoscopic images via the fusion of residual blocks, including alpha dropouts (αDO) and auxiliary fusing layers.

To automatically diagnose colon disorders from medical images, this work explores the use of a fused deeplearning model that incorporates the EfficientNetB0, MobileNetV2, and ResNet50V2 architectures. By integrating these features, the fused model aims to improve the classification accuracy and robustness for various colon diseases. The proposed model incorporates an auxiliary fusion layer and a fusion residual block. By combining diverse features through an auxiliary fusion layer, the network can create more comprehensive and richer representations, capturing intricate patterns that might be missed by single-source processing. The fusion residual block incorporates residual connections, which help mitigate the vanishing gradient problem. By adding the input of the block directly to its output, these connections facilitate better gradient flow during backpropagation, allowing for deeper and more stable training. A wide range of endoscopic images are used to assess the proposed model, offering an accurate depiction of various disease scenarios.

The proposed model, with an auxiliary fusion layer and residual blocks, exhibited an enormous reduction in overfitting and performance saturation. The proposed model achieved an impressive 98.03% training accuracy and 97.90% validation accuracy after evaluation, outperforming the majority of typically trained DCNNs in terms of efficiency and accuracy.

The proposed method developed a lightweight model that correctly identifies disorders of the gastrointestinal (GI) tract by combining advanced techniques, including feature fusion, residual learning, and self-normalization.