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2000
Volume 33, Issue 1
  • ISSN: 0929-8673
  • E-ISSN: 1875-533X

Abstract

Introduction

This study aimed to investigate the impact of coronavirus disease 2019 (COVID-19) syndrome on various aspects of acne exacerbation. Additionally, we aimed to explore the risk factors for acne exacerbation after COVID-19 syndrome.

Methods

A total of 211 subjects with acne were enrolled, and their key demographic characteristics and lifestyle factors were recorded. They were asked whether acne exacerbation occurred after COVID-19 syndrome, as well as the latency of exacerbation, the exacerbation location, and the form of skin lesions. The risk factors were analyzed using the Cox proportional hazard regression model. Overall, 41.2% of cases reported exacerbation of acne after COVID-19 syndrome. Age was found to be a protective factor. Additionally, sufficient fruit intake may slightly prevent exacerbation. For participants engaging in daily physical exercise, the likelihood of exacerbation was significantly increased after COVID-19 syndrome.

Results

The probability of exacerbation was significantly higher if an acne itch was present. Patients who experienced exacerbation in the chin area were more likely to develop acne-induced anxiety. Males had a higher risk of aggravation of the cyst form. Interestingly, those with lower education levels were more likely to have aggravation in the right cheek after COVID-19 syndrome. Moreover, physical exercise might prevent aggravation in the front or back areas.

Conclusion

Finally, fish intake of ≥240 g per week was related to the aggravation of the hard nodule form. In conclusion, age and adequate fruit intake may play a protective role, while acne itch and daily exercise may be risk factors for acne exacerbation.

© 2026 Bentham Science Publishers
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2024-12-27
2025-12-31

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References

  1. BoufidouF. MedićS. LampropoulouV. SiafakasN. TsakrisA. AnastassopoulouC. SARS-CoV-2 reinfections and long COVID in the post-omicron phase of the pandemic.Int. J. Mol. Sci.202324161296210.3390/ijms24161296237629143
     [Google Scholar]
  2. SukochevaO.A. MaksoudR. BeerakaN.M. MadhunapantulaS.V. SinelnikovM. NikolenkoV.N. NeganovaM.E. KlochkovS.G. Amjad KamalM. StainesD.R. Marshall-GradisnikS. Analysis of post COVID-19 condition and its overlap with myalgic encephalomyelitis/chronic fatigue syndrome.J. Adv. Res.20224017919610.1016/j.jare.2021.11.01336100326
     [Google Scholar]
  3. YaoY. SunL. LuoJ. QiW. ZuoX. YangZ. The effect of long-term COVID-19 infection on maternal and fetal complications: A retrospective cohort study conducted at a single center in China.Sci. Rep.20241411727310.1038/s41598‑024‑68184‑239068277
     [Google Scholar]
  4. ZhuN. ZhangD. WangW. LiX. YangB. SongJ. ZhaoX. HuangB. ShiW. LuR. NiuP. ZhanF. MaX. WangD. XuW. WuG. GaoG.F. TanW. China Novel Coronavirus Investigating and Research Team A novel coronavirus from patients with pneumonia in China, 2019.N. Engl. J. Med.2020382872773310.1056/NEJMoa200101731978945
     [Google Scholar]
  5. YangL. XuH.Y. WangY. Diagnostic and therapeutic strategies of lung cancer patients during the outbreak of 2019 novel coronavirus disease (COVID-19).Zhonghua Zhong Liu Za Zhi202042429229532118394
     [Google Scholar]
  6. VillaniA. AnnunziataM.C. MegnaM. ScalvenziM. FabbrociniG. Long-term results of teledermatology for acne patients during COVID-19 pandemic.J. Cosmet. Dermatol.20222141356135710.1111/jocd.1480535090188
     [Google Scholar]
  7. DrozdowskiR. GronbeckC. FengH. Mask-related acne in the COVID-19 pandemic: An analysis of Twitter posts and influencers.Clin. Exp. Dermatol.202146594394510.1111/ced.1460833577082
     [Google Scholar]
  8. HadžavdićA. Bukvić MokosZ. Maskne: A new entity in the covid-19 pandemic.Acta Dermatovenerol. Croat.202129314815334990343
     [Google Scholar]
  9. CretuS. DascaluM. SalavastruC.M. Acne care in health care providers during the COVID-19 pandemic: A national survey.Dermatol. Ther.20223510e1575310.1111/dth.1575336190007
     [Google Scholar]
  10. PietrzykS.J. KielczynskaE. KowalczykM. MazurekM. DomagalaZ.A. Potential impacts of prolonged face mask use on temporomandibular joint health as neglected lifestyle repercussions of COVID-19 pandemic-a narrative review.Medicina2024609146810.3390/medicina6009146839336509
     [Google Scholar]
  11. DamianiG. GironiL.C. GradaA. KridinK. FinelliR. BujaA. BragazziN.L. PigattoP.D.M. SavoiaP. COVID-19 related masks increase severity of both acne (maskne) and rosacea (mask rosacea): Multi-center, real-life, telemedical, and observational prospective study.Dermatol. Ther.2021342e1484810.1111/dth.1484833533563
     [Google Scholar]
  12. DamianiG. FinelliR. KridinK. PacificoA. BujaA. BragazziN.L. MalagoliP. SavoiaP. GironiL.C. GradaA. ConicR.R. LinderD. MicaliG. PigattoP.D. Young Dermatologists Italian Network Masks trigger facial seborrheic dermatitis and psoriasis: Evidence from a multicenter, case-control study during COVID-19 pandemic.Ital. J. Dermatol. Venereol.2022157541942310.23736/S2784‑8671.22.07246‑235829673
     [Google Scholar]
  13. KabiA.K. PalM. GujjarappaR. MalakarC.C. RoyM. Overview of Hydroxychloroquine and Remdesivir on severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2).J. Heterocycl. Chem.202210.1002/jhet.454135942205
     [Google Scholar]
  14. ChengY.F. ZhaoH. LiJ. LipaK.E. XieH.F. WangB. HuangY.X. Factors aggravating acne vulgaris during the COVID-19 pandemic in China: A web-based cross-sectional survey.Eur. Rev. Med. Pharmacol. Sci.202226197305731236263543
     [Google Scholar]
  15. DaniA. EseonuA. BibeeK. Risk factors for the development of acne in healthcare workers during the COVID-19 pandemic.Arch. Dermatol. Res.202231541067107010.1007/s00403‑022‑02434‑z36357553
     [Google Scholar]
  16. YaleK. ElsanadiR. GhigiA. ZhengK. GorenA. MesinkovskaN.A. Androgens and women: COVID-19 outcomes in women with acne vulgaris, polycystic ovarian syndrome, and hirsutism.Int. J. Dermatol.2021607e267e26810.1111/ijd.1547333650165
     [Google Scholar]
  17. YıldırımF. MertB. ÇağatayE.Y. AksoyB. Predictors of quality of life in adults and adolescents with acne.Indian J. Dermatol.202267323924610.4103/ijd.IJD_781_2036386112
     [Google Scholar]
  18. Ramos-e-SilvaM. CarneiroS.C. Acne vulgaris: Review and guidelines.Dermatol. Nurs.2009212636819507372
     [Google Scholar]
  19. ConfortiC. AgozzinoM. EmendatoG. FaiA. FicheraF. MarangiG.F. NeaguN. PellacaniG. PersichettiP. SegretoF. ZalaudekI. DianzaniC. Acne and diet: A review.Int. J. Dermatol.202261893093410.1111/ijd.1586234423427
     [Google Scholar]
  20. ChlebusE. ChlebusM. Factors affecting the course and severity of adult acne. Observational cohort study.J. Dermatolog. Treat.201728873774410.1080/09546634.2017.132950028489484
     [Google Scholar]
  21. Dall’OglioF. NascaM.R. FiorentiniF. MicaliG. Diet and acne: Review of the evidence from 2009 to 2020.Int. J. Dermatol.202160667268510.1111/ijd.1539033462816
     [Google Scholar]
  22. HuangX. ZhangJ. LiJ. ZhaoS. XiaoY. HuangY. JingD. ChenL. ZhangX. SuJ. KuangY. ZhuW. ChenM. ChenX. ShenM. Daily intake of soft drinks and moderate-to-severe acne vulgaris in Chinese adolescents.J. Pediatr.2019204256262.e310.1016/j.jpeds.2018.08.03430274928
     [Google Scholar]
  23. MarkovicM. SoldatovicI. BjekicM. Sipetic-GrujicicS. Adolescents’ self perceived acne-related beliefs: From myth to science.An. Bras. Dermatol.201994668469010.1016/j.abd.2019.02.00531789254
     [Google Scholar]
  24. SuthipinittharmP. NoppakunN. KulthananK. JiamtonS. RajatanavinN. AunhachokeK. SindhavanondaJ. AkraphanR. ManapajonA. Opinions and perceptions on acne: A community-based questionnaire study in Thai students.J. Med. Assoc. Thai.201396895295923991603
     [Google Scholar]
  25. WisuthsarewongW. NitiyaromR. KanchanapenkulD. ArunkajohnaskS. LimphokaP. BoonchaiW. Acne beliefs, treatment-seeking behaviors, information media usage, and impact on daily living activities of Thai acne patients.J. Cosmet. Dermatol.20201951191119510.1111/jocd.1313231498553
     [Google Scholar]
  26. BaldwinH. TanJ. Effects of diet on acne and its response to treatment.Am. J. Clin. Dermatol.2021221556510.1007/s40257‑020‑00542‑y32748305
     [Google Scholar]
  27. KhayefG. YoungJ. Burns-WhitmoreB. SpaldingT. Effects of fish oil supplementation on inflammatory acne.Lipids Health Dis.201211116510.1186/1476‑511X‑11‑16523206895
     [Google Scholar]
  28. ŁożyńskaK. GłąbskaD. Association between nutritional behaviours and acne-related quality of life in a population of polish male adolescents.Nutrients20221413267710.3390/nu1413267735807855
     [Google Scholar]
  29. Han, Y.; Sun, Y.; Wang, S. Effect of targeted beauty nursing on mood and DLQI score of acne patients.Chinese J. Aesthetic Med.2019288
     [Google Scholar]
  30. Chen, S.P.; Liang, C.; Zhang, Y.Z.; Zheng, K.B. Effects of cotton sheet moxibustion combined with prick and cupping on pain degree, serum substance Plevel and DLQI score in patients with acute herpes zoster.CABI Databases202217557457710.13350/j.cjpb.220516
     [Google Scholar]
/content/journals/cmc/10.2174/0109298673345685241114104703
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Post-COVID-19 Syndrome-associated Risk Factors for Acne Exacerbation
Curr. Med. Chem. 33, 210 (2026); https://doi.org/10.2174/0109298673345685241114104703
/content/journals/cmc/10.2174/0109298673345685241114104703
/content/journals/cmc/10.2174/0109298673345685241114104703
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  • Article Type:     Research Article
Keyword(s): acne exacerbation; COVID-19; Cox proportional hazard regression model; health fitness; SARS-CoV-2; wald backwards method

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