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2000
Volume 23, Issue 1
  • ISSN: 1570-162X
  • E-ISSN: 1873-4251

Abstract

Anti-Retroviral Therapy (ART) is a fundamental principle in the management of Human immunodeficiency virus (HIV) infection, significantly improving the quality of life for individuals living with the virus. However, the success of ART crucially depends on patient adherence to complex medication regimens that come with the therapy. Patients must meticulously adhere to their prescribed treatment plans to maintain viral suppression and prevent the progression of HIV. Medication adherence, a multifaceted challenge in healthcare, becomes particularly entangled within the realm of ART. Patients are often prescribed a combination of antiretroviral medications, each with unique dosing schedules and dietary requirements as instructed by the physician. For individuals with varying levels of health literacy, language proficiency, and cultural backgrounds, comprehending and adhering to these regimens can be overwhelming and challenging. Non-adherence to these medications can result in treatment failure, drug resistance, and compromised health outcomes that burden the healthcare systems. In that perspective, the role of pictograms as visual aids emerges as part and parcel of patient education and counseling within healthcare systems. Pictograms are graphical representations of concepts or actions designed to transcend linguistic and literacy barriers. When used in conjunction with ART, they simplify complex medication instructions, empower patients with knowledge, and improve adherence. Generally, the role of pictograms in supporting medication adherence and patient counseling in antiretroviral therapy is a powerful testament that serves a purpose in bridging communication and literacy gaps within the healthcare systems. By simplifying complex medication regimens, empowering patients with knowledge, and fostering adherence, pictograms contribute to better health outcomes and the overall success of ART. As healthcare providers and systems continue to harness the potential of pictograms, patient education and adherence in the management of HIV and other chronic conditions stand to be greatly enhanced.

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2024-12-03
2025-09-28

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References

  1. JohnsonAM BrimhallAS JohnsonET HodgsonJ DidericksenK PyeJ HarmonGC SewellKB A systematic review of the effectiveness of patient education through patient portals.JAMIA Open.202361ooac08510.1093/jamiaopen/ooac085
     [Google Scholar]
  2. CarmanKL. DardessP MaurerM SofaerS AdamsK BechtelC SweeneyJ Patient and family engagement: a framework for understanding the elements and developing interventions and policies.Health Aff20133222233110.1377/hlthaff.2012.1133
     [Google Scholar]
  3. SmithD.A. Situating Wikipedia as a health information resource in various contexts: A scoping review.PLoS One2020152e022878610.1371/journal.pone.022878632069322
     [Google Scholar]
  4. HeplerC.D. StrandL.M. Opportunities and responsibilities in pharmaceutical care.Am. J. Hosp. Pharm.19904735335432316538
     [Google Scholar]
  5. SzeinbachS.L. BarnesJ.H. SummersK.H. The role of pharmacist counselling in patient adherence to oral antidiabetic medications: a systematic review.Ann. Pharmacother.200236121862186712452745
     [Google Scholar]
  6. Al HamidA. GhalebM. AljadheyH. AslanpourZ. Effectiveness of pharmacist-led counselling in improving medication adherence and outcomes in patients with chronic diseases: A systematic review and meta-analysis.Diseases2018624029783726
     [Google Scholar]
  7. HaynesR.B. McDonaldH.P. GargA.X. Improving medication adherence in chronic illness: a review of systematically applied interventions.Clin Res Methodol.200229611521161
     [Google Scholar]
  8. GazmararianJA. Health literacy and knowledge of chronic disease.Patient Educ Couns.200351326775
     [Google Scholar]
  9. FordN. DarderM. SpelmanT. Early adherence to antiretroviral therapy and all-cause mortality among HIV-infected individuals: A systematic review and meta-analysis.AIDS201024410611070
     [Google Scholar]
  10. WHOAdherence to long-term therapies: evidence for action.GenevaWorld Health Organization2003
     [Google Scholar]
  11. DiMatteoM.R. Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research.Med. Care200442320020910.1097/01.mlr.0000114908.90348.f915076819
     [Google Scholar]
  12. VrijensB. De GeestS. HughesD.A. PrzemyslawK. DemonceauJ. RupparT. DobbelsF. FargherE. MorrisonV. LewekP. MatyjaszczykM. MsheliaC. ClyneW. AronsonJ.K. UrquhartJ. A new taxonomy for describing and defining adherence to medications.Br. J. Clin. Pharmacol.201273569170510.1111/j.1365‑2125.2012.04167.x22486599
     [Google Scholar]
  13. BrownM.T. BussellJ.K. Medication adherence: WHO cares?Mayo Clin. Proc.201186430431410.4065/mcp.2010.057521389250
     [Google Scholar]
  14. LeyP Doctor-patient communication: some quantitative estimates of the role of cognitive factors in non-compliance.J. Hypertens.198531S515
     [Google Scholar]
  15. PraskaJ.L. KripalaniS. SerightA.L. JacobsonT.A. Identifying and assisting low-literacy patients with medication use: a survey of community pharmacies.Ann. Pharmacother.20053991441144510.1345/aph.1G09416046489
     [Google Scholar]
  16. StinglG. Anti-retroviral therapy in HIV-1-infected persons: concepts and strategies.Curr. Probl. Dermatol.19891825026810.1159/0004168632663369
     [Google Scholar]
  17. JimmyB. JoseJ. Patient medication adherence: measures in daily practice.Oman Med. J.201126315515910.5001/omj.2011.3822043406
     [Google Scholar]
  18. GolinC.E. DiMatteoM.R. GelbergL. The role of patient participation in the doctor visit. Implications for adherence to diabetes care.Diabetes Care199619101153116410.2337/diacare.19.10.11538886566
     [Google Scholar]
  19. GandhiR.T. BedimoR. HoyJ.F. LandovitzR.J. SmithD.M. EatonE.F. LehmannC. SpringerS.A. SaxP.E. ThompsonM.A. BensonC.A. BuchbinderS.P. del RioC. EronJ.J.Jr GünthardH.F. MolinaJ.M. JacobsenD.M. SaagM.S. Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2022 recommendations of the International Antiviral Society–USA panel.JAMA20233291638410.1001/jama.2022.2224636454551
     [Google Scholar]
  20. GiromettiN. LanderF. McOwanA. NwokoloN. BoffitoM. WhitlockG. Rapid ART start in early HIV infection: Time to viral load suppression and retention in care in a London cohort.HIV Med.202021961361510.1111/hiv.1290032869951
     [Google Scholar]
  21. BarryM. MulcahyF. BackD.J. Antiretroviral therapy for patients with HIV disease.Br. J. Clin. Pharmacol.199845322122810.1046/j.1365‑2125.1998.00673.x9517365
     [Google Scholar]
  22. Menéndez-AriasL. DelgadoR. Update and latest advances in antiretroviral therapy.Trends Pharmacol. Sci.2022431162910.1016/j.tips.2021.10.00434742581
     [Google Scholar]
  23. PetersonP.N. ShetterlyS.M. ClarkeC.L. BekelmanD.B. ChanP.S. AllenL.A. MatlockD.D. MagidD.J. MasoudiF.A. Health literacy and outcomes among patients with heart failure.JAMA2011305161695170110.1001/jama.2011.51221521851
     [Google Scholar]
  24. WawrzyniakA.J. OwnbyR.L. McCoyK. Waldrop-ValverdeD. Health literacy: impact on the health of HIV-infected individuals.Curr. HIV/AIDS Rep.201310429530410.1007/s11904‑013‑0178‑424222474
     [Google Scholar]
  25. T SimelaneP. S SimelaneM. Y AmoatengA. Barriers and facilitators to adherence for antiretroviral therapy: the perspectives of patients from a wellness center in the Mpumalanga Province, South Africa.Afr. Health Sci.202222345546210.4314/ahs.v22i3.4936910408
     [Google Scholar]
  26. SedehF.B. Arvid Simon HenningM. MortensenO.S. JemecG.B.E. IblerK.S. Communicating with patients through pictograms and pictures – a scoping review.J. Dermatolog. Treat.20223362730273710.1080/09546634.2022.206879035440279
     [Google Scholar]
  27. WangT. VossJ.G. Effectiveness of pictographs in improving patient education outcomes: a systematic review.Health Educ. Res.202136194010.1093/her/cyaa04633331898
     [Google Scholar]
  28. FongO.W. HoC.F. FungL.Y. LeeF.K. TseW.H. YuenC.Y. SinK.P. WongK.H. Determinants of adherence to highly active antiretroviral therapy (HAART) in Chinese HIV/AIDS patients.HIV Med.20034213313810.1046/j.1468‑1293.2003.00147.x12702134
     [Google Scholar]
  29. KalichmanS.C. BenotschE. SuarezT. CatzS. MillerJ. RompaD. Health literacy and health-related knowledge among persons living with HIV/AIDS.Am. J. Prev. Med.200018432533110.1016/S0749‑3797(00)00121‑510788736
     [Google Scholar]
  30. PeregrinT. Picture this: visual cues enhance health education messages for people with low literacy skills.J. Am. Diet. Assoc.20101105Suppl.S28S3210.1016/j.jada.2010.03.00520399294
     [Google Scholar]
  31. CloutierM. VaillancourtR. PynnD. WadeJ. PrestonC. TurpinP.M. HansraA. Design and development of culture-specific pictograms for type 2 diabetes mellitus education and counselling.Can. J. Diabetes201438637939210.1016/j.jcjd.2014.03.01025028197
     [Google Scholar]
  32. MontagneM. Pharmaceutical pictograms: A model for development and testing for comprehension and utility.Res. Social Adm. Pharm.20139560962010.1016/j.sapharm.2013.04.00323680485
     [Google Scholar]
  33. SletvoldH. SagmoL.A.B. TorheimE.A. Impact of pictograms on medication adherence: A systematic literature review.Patient Educ. Couns.202010361095110310.1016/j.pec.2019.12.01831924384
     [Google Scholar]
  34. DowseR. EhlersM.S. Pictograms in pharmacy.Int. J. Pharm. Pract.20116210911810.1111/j.2042‑7174.1998.tb00924.x37232546
     [Google Scholar]
  35. DowseR. EhlersM. Pictograms for conveying medicine instructions: comprehension in various South African language groups.S. Afr. J. Sci.200410011687693
     [Google Scholar]
  36. WorkD.R. Improving drug labels with pictograms.Int Pharm J.19904153157
     [Google Scholar]
  37. DowseR. Designing and reporting pictogram research: Problems, pitfalls and lessons learnt.Res. Social Adm. Pharm.20211761208121510.1016/j.sapharm.2020.08.01332873526
     [Google Scholar]
  38. VaillancourtR TruongY KarmaliS KraftA ManjiS VillarrealG PouliotA Instructions for masking the taste of medication for children: Validation of a pictogram tool.Can Pharm J20171501525910.1177/1715163516669383
     [Google Scholar]
  39. LeemanJ. ChangY.K. LeeE.J. VoilsC.I. CrandellJ. SandelowskiM. Implementation of antiretroviral therapy adherence interventions: a realist synthesis of evidence.J. Adv. Nurs.20106691915193010.1111/j.1365‑2648.2010.05360.x20707822
     [Google Scholar]
  40. NieuwlaatR. WilczynskiN. NavarroT. HobsonN. JefferyR. KeepanasserilA. AgoritsasT. MistryN. IorioA. JackS. SivaramalingamB. IsermanE. MustafaR.A. JedraszewskiD. CotoiC. HaynesR.B. Interventions for enhancing medication adherence.Cochrane Libr.2014201411CD00001110.1002/14651858.CD000011.pub425412402
     [Google Scholar]
  41. DowseR. Pharmacy students’ opinion of the routine use of pharmaceutical pictograms on a health care train serving rural limited literacy patients.Int. J. Pharm. Pract.202331442343010.1093/ijpp/riad03037232546
     [Google Scholar]
  42. ShetA. CostaA.D. KumarasamyN. RodriguesR. RewariB.B. AshornP. ErikssonB. DiwanV. Effect of mobile telephone reminders on treatment outcome in HIV: evidence from a randomised controlled trial in India.BMJ2014347aug06 2g597810.1136/bmj.g597825742320
     [Google Scholar]
  43. OmachiT.A. SarkarU. YelinE.H. BlancP.D. KatzP.P. Lower health literacy is associated with poorer health status and outcomes in chronic obstructive pulmonary disease.J. Gen. Intern. Med.2013281748110.1007/s11606‑012‑2177‑322890622
     [Google Scholar]
  44. WilhelmsenN.C. ErikssonT. Medication adherence interventions and outcomes: an overview of systematic reviews.Eur. J. Hosp. Pharm. Sci. Pract.201926418719210.1136/ejhpharm‑2018‑00172531338165
     [Google Scholar]
  45. BarrosI.M.C. AlcântaraT.S. MesquitaA.R. SantosA.C.O. PaixãoF.P. LyraD.P.Jr The use of pictograms in the health care: A literature review.Res. Social Adm. Pharm.201410570471910.1016/j.sapharm.2013.11.00224332470
     [Google Scholar]
  46. MenonD.D. JoyJ.M. PaulA. ReddyS.A. RajE.A. KrishnanJ.B. VilakkathalaR. Effectiveness of pictograms in patients or caregivers in healthcare settings: a systematic review.J. Pharm. Health Serv. Res.202112460761410.1093/jphsr/rmab049
     [Google Scholar]
  47. ReijnenE. Laasner VogtL. FiechterJ.P. KühneS.J. MeisterN. VenzinC. AebersoldR. Well-designed medical pictograms accelerate search.Appl. Ergon.202210310379910.1016/j.apergo.2022.10379935588557
     [Google Scholar]
  48. MalhotraR. TanY.W. SuppiahS.D. TayS.S.C. TanN.C. LiuJ. KohG.C.H. ChanA. VaillancourtR. Pharmaceutical pictograms: User-centred redesign, selection and validation.PEC Innov.2023210011610.1016/j.pecinn.2022.10011637214531
     [Google Scholar]
  49. Epidemiological fact sheet – HIV statistics, globally and by WHO region.2022Available from: https://www.who.int/teams/global-hiv-hepatitis-and-stis-programmes/hiv/strategic-information/hiv-data-and-statistics/
/content/journals/chr/10.2174/011570162X330392241127084502
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Augmenting Adherence: Improving Medication Compliance and Patient Education in Anti-Retroviral Therapy through Graphical Representation
Cur. HIV Res. 23, 14 (2025); https://doi.org/10.2174/011570162X330392241127084502
/content/journals/chr/10.2174/011570162X330392241127084502
/content/journals/chr/10.2174/011570162X330392241127084502
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  • Article Type:     Review Article
Keyword(s): antiretroviral therapy; health literacy; healthcare system; medication adherence; patient counselling; patient education; Pictograms

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