The Use of Microwave For One-pot Reductive Amination

A variety of reactions can now be conducted in microwave ovens. Generally, equal or better yields are obtained when microwave heating is being utilized for a reaction compared to the use of conventional heating. One area of organic synthesis where microwave conditions is being used more is in the formation of secondary and tertiary amines. This review will highlight the use of microwave heating in one-pot formation of primarily secondary aryl amines with a few examples of formation of primary and tertiary amines being descussed.