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2000
Volume 20, Issue 5
  • ISSN: 1574-8855
  • E-ISSN: 2212-3903

Abstract

Currently, studies on various natural products that aid in wound healing have seen significant growth. Betulin and its derivative, betulinic acid, are triterpenes abundant in the leaves and barks of certain species, such as birch, which has been of particular interest. Clinical and preclinical studies have demonstrated their ability to accelerate wound healing, as well as other properties such as antimicrobial, anti-inflammatory action, and anti-cancer properties, and beneficial effects on HIV, diabetes mellitus, and cardiovascular disorders. However, further research focusing exclusively on betulin and betulinic acid is needed to better understand its therapeutic potential and develop new medications for effective management. These advancements could greatly enhance the treatment of wounds, skin lesions and other diseases, offering more effective and safer therapeutic options to improve the quality of life of the population.

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2024-06-13
2025-09-23

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The Role of Betulin and its Derivative in Wound Healing and their Clinical Properties
Curr Drug Ther 20, 608 (2025); https://doi.org/10.2174/0115748855311705240530073557
/content/journals/cdth/10.2174/0115748855311705240530073557
/content/journals/cdth/10.2174/0115748855311705240530073557
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  • Article Type:     Review Article
Keyword(s): betula; betulin; betulinic acid; cicatrix; triterpenes; Wound healing

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