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2000
Volume 18, Issue 1
  • ISSN: 2589-9775
  • E-ISSN: 2589-9783

Abstract

Introduction

, commonly known as the Mexican poppy, has earned significant recognition in the traditional healing systems of the Eastern Indian region, where it has been used for centuries as a folk remedy for a variety of diseases. The study was based on search or identified through Pubmed, Google Scholar, Science Direct, .

Meta-analysis

Phytochemical analysis has demonstrated that the alkaloids present in exhibit potent antimicrobial properties, making the plant an effective natural remedy for treating infections caused by bacteria, fungi, and viruses. In addition, the plant’s flavonoids and phenolic compounds are recognized for their strong anti-inflammatory and antioxidant activities, which play a crucial role in alleviating pain, reducing inflammation, and promoting tissue repair. Furthermore, has shown significant analgesic effects, which support its traditional use as a pain reliever. The integration of ethnobotanical knowledge with modern pharmacological research is essential for fully unlocking the therapeutic potential of .

Future Scope

Future studies must focus on comprehensive clinical trials, toxicological evaluations, and in-depth mechanistic investigations to validate the efficacy and safety of in human populations.

Conclusion

This review highlights the urgent need for further research to bridge the gap between traditional knowledge and contemporary scientific understanding. By advancing the study of , there is a significant opportunity to develop novel, cost-effective, and sustainable therapeutic agents that could serve as alternatives to synthetic drugs, particularly in regions where access to modern healthcare is limited.

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References

  1. Cancer IA for R on, Organization WH Some traditional herbal medicines, some mycotoxins, naphthalene and styrene.World Health Organization2002
    [Google Scholar]
  2. BlumenthalM. The german commission e monograph system for phytomedicines: A model for regulatory reform in the United States.In: Phytomedicines of Europe ACS Symposium SeriesAmerican Chemical Society199869130610.1021/bk‑1998‑0691.ch003
    [Google Scholar]
  3. OrganizationW.H. WHO monographs on selected medicinal plants.World Health Organization19992
    [Google Scholar]
  4. GregoryP. JellinJ. BatzF. The natural medicines comprehensive database.Pharm. Lett.2013
    [Google Scholar]
  5. TagH. DasA.K. LoyiH. Anti-inflammatory plants used by the Khamti tribe of Lohit district in eastern Arunachal Pradesh, India.Nat. Prod. Radiance20076334340
    [Google Scholar]
  6. MukherjeeP.K. BahadurS. HarwanshR.K. BiswasS. BanerjeeS. Paradigm shift in natural product research: Traditional medicine inspired approaches.Phytochem. Rev.201716580382610.1007/s11101‑016‑9489‑6
    [Google Scholar]
  7. AlamA. KhanA. Argemone mexicana L.: A weed with versatile medicinal and pharmacological applications.Ann. Phytomed.20209
    [Google Scholar]
  8. JoshiN. BhattS. DhyaniD. NainJ. Phytochemical screening of secondary metabolites of Argemone mexicana Linn. Flowers.Int. J. Curr. Pharm. Res.20135144147
    [Google Scholar]
  9. MalikC. PriyaM.J. PradhanS. SharmaC. Phytochemistry and pharmacology of Argemone mexicana Linn – An Indian medicinal plant.Res J Pharmacol Phytochem2023151273210.52711/0975‑4385.2023.00005
    [Google Scholar]
  10. PathakR. Medicinal property and ethnopharmacological activities of Argemone mexicana: An overview.Ann. Rom. Soc. Cell Biol.202125316151641
    [Google Scholar]
  11. PatockaJ. Ovando-MartínezM. NavratilovaZ. Argemone mexicana L. (Papaveraceae): Chemistry, pharmacology, and toxicology.Phytochem. Rev.20242341167118210.1007/s11101‑024‑09918‑y
    [Google Scholar]
  12. SharanappaR. Ant profile, phytochemistry and pharmacology of Argemone mexicana linn. A review.Int. J. Pharm. Pharm. Sci.2014674653
    [Google Scholar]
  13. SiddiquiI.A. ShaukatS.S. KhanG.H. ZakiM.J. Evaluation of Argemone mexicana for control of root‐infecting fungi in tomato.J. Phytopathol.2002150632132910.1046/j.1439‑0434.2002.00762.x
    [Google Scholar]
  14. MariodA.A. SaeedM.M.E. HusseinI. Chapter 2 - Argemone mexicana (Argemone Seed).In: Unconventional Oilseeds and Oil Sources.Academic Press2017912
    [Google Scholar]
  15. ThoratV.H. GhorpadeS. Argemone mexicana Linn. having medicinal property.Int J Pharmacogn2018528290
    [Google Scholar]
  16. IsrailovI.A. YunusovM.S. Alkaloids of four species of Argemone.Chem. Nat. Compd.198622218919210.1007/BF00574736
    [Google Scholar]
  17. SantosA.C. AdkilenP. The alkaloids of Argemone mexicana.J. Am. Chem. Soc.19325472923292410.1021/ja01346a037
    [Google Scholar]
  18. HaisováK. SlavíkJ. On the minor alkaloids from Argemone mexicana L.Collect. Czech. Chem. Commun.19754051576157810.1135/cccc19751576
    [Google Scholar]
  19. ChangY.C. ChangF.R. KhalilA.T. HsiehP.W. WuY.C. Cytotoxic benzophenanthridine and benzylisoquinoline alkaloids from Argemone mexicana.Z. Naturforsch. C J. Biosci.2003587-852152610.1515/znc‑2003‑7‑813 12939038
    [Google Scholar]
  20. BentleyK.W. β-Phenylethylamines and the isoquinoline alkaloids (July 1999 to June 2000).Nat. Prod. Rep.200118214817010.1039/a909672h 11336286
    [Google Scholar]
  21. BhattacharjeeI. ChatterjeeS.K. ChatterjeeS. ChandraG. Antibacterial potentiality of Argemone mexicana solvent extracts against some pathogenic bacteria.Mem. Inst. Oswaldo Cruz2006101664564810.1590/S0074‑02762006000600011 17072477
    [Google Scholar]
  22. ChangY.C. HsiehP.W. ChangF.R. Two new protopines argemexicaines A and B and the anti-HIV alkaloid 6-acetonyldihydrochelerythrine from formosan Argemone mexicana.Planta Med.200369214815210.1055/s‑2003‑37710 12624820
    [Google Scholar]
  23. SinghS. SinghA. JaiswalJ. Antifungal activity of the mixture of quaternary alkaloids isolated from Argemone mexicana against some phytopathogenic fungi.Arch. Phytopathol. Pflanzenschutz201043876977410.1080/03235400802176159
    [Google Scholar]
  24. SinghA. SinghS. SinghS. Fungal spore germination inhibition by alkaloids dehydrocorydalmine and oxyberberine.J. Plant Prot. Res.20094934910.2478/v10045‑009‑0046‑9
    [Google Scholar]
  25. GuptaR.S. DixitV.P. DobhalM.P. Antifertility studies of isoquinoline alkaloids with special emphasis on structure activity relationship.Fitoterapia19906116771
    [Google Scholar]
  26. ShammaM. The isoquinoline alkaloids chemistry and pharmacology.Elsevier201225
    [Google Scholar]
  27. NakkadyS. ShammaM. Studies on the chemical constitution of Argemone mexicana.Egypt. J. Pharm. Sci.1988291–45361
    [Google Scholar]
  28. TripathiP.N. Alkaloids of Argemone Mexican A.Orient. J. Chem.1999151
    [Google Scholar]
  29. FletcherM.T. TakkenG. BlaneyB.J. AlbertsV. Isoquinoline alkaloids and keto-fatty acids of Argemone ochroleuca and A. mexicana (mexican poppy) seed. I. An assay method and factors affecting their concentration.Aust. J. Agric. Res.199344226527510.1071/AR9930265
    [Google Scholar]
  30. HussainS.F. NakkadyS. KhanL. ShammaM. Oxyhydrastinine, an isoquinolone alkaloid from the papaveraceae.Phytochemistry198322131932010.1016/S0031‑9422(00)80125‑9
    [Google Scholar]
  31. RahmanA. AhmadV.U. Handbook of Natural Products Data: Isoquinoline alkaloids.Elsevier1990
    [Google Scholar]
  32. SukumarD. NambiR.A.S.N. Studies on the leaves of Agremonemexicana.Fitoterapia198455325353
    [Google Scholar]
  33. BoseB.C. VijayvargiyaR. SaifiA.Q. SharmaS.K. Chemical and pharmacological studies on Argemone mexicana.J. Pharm. Sci.196352121172117510.1002/jps.2600521216 14088969
    [Google Scholar]
  34. YadavR.N.S. AgarwalaM. Phytochemical analysis of some medicinal plants.J. Phytol.2011312
    [Google Scholar]
  35. HarborneJ.B. WilliamsC.A. Flavonoids in the seeds of Argemone mexicana: A reappraisal.Phytochemistry19832261520152110.1016/S0031‑9422(00)84057‑1
    [Google Scholar]
  36. RahmanW. IlyasM. Flower Pigments. Flavonoids from Argemone mexicana linn. (Papaveraceae).J. Org. Chem.196227115315510.1021/jo01048a037
    [Google Scholar]
  37. SinghS. SinghT. PandeyV.B. Constituents of Argemone species.J. Indian Chem. Soc.201188275276
    [Google Scholar]
  38. SinghS. PandeyV.B. SinghT.D. Alkaloids and flavonoids of Argemone mexicana.Nat. Prod. Res.2012261162110.1080/14786419.2010.529809 21722040
    [Google Scholar]
  39. BhardwajD.K. BishtM.S. JainR.K. MunjalA. Phenolics from the seeds of Argemone mexicana.Phytochemistry19822182154215610.1016/0031‑9422(82)83078‑1
    [Google Scholar]
  40. DwivediD.S. DwivediD. KapadiaR. Argemone Mexicana Linn. (Ghamoya) : A weed having great therapeutic values in folk remedies.Pharm. Rev.2008
    [Google Scholar]
  41. BadamiR.C. GunstoneF.D. Vegetable oils. X.-Examination of component acids of Argemone mexicana seed oil by reversed‐phase chromatography.J. Sci. Food Agric.196213425525710.1002/jsfa.2740130407
    [Google Scholar]
  42. SharmaD. SharmaL. Argemone mexicana a hidden medicinal plant and to evaluate its edibility.In: Futuristic Trends in Agriculture Engineering and Food Sciences.IndiaIIP Series202427328310.58532/V3BCAG13P1CH22
    [Google Scholar]
  43. BrahmachariG. GoraiD. RoyR. Argemone mexicana: Chemical and pharmacological aspects.Rev. Bras. Farmacogn.201323355957510.1590/S0102‑695X2013005000021
    [Google Scholar]
  44. SinghR. ChaubeyN. MishraR.K. Evaluation of anti-asthmatic activity of ethanolic extract of Argemone mexicana stems.Saudi J Med Pharm Sci202171394410.36348/sjmps.2021.v07i01.007
    [Google Scholar]
  45. PawarR.J. GovilkarS.A. AhireS.B. BairagiV.A.A. Review: Argemone mexicana is an indigenous herb.Int J Pharmacogn202076137143
    [Google Scholar]
  46. VarunS. SellappaS. In vitro screening of phytochemicals and anticancer activity of Argemone Mexicana leaf extract.World J. Pharm. Res.201438547556
    [Google Scholar]
  47. GaliK.G.K. RamakrishnanG. KothaiR. JaykarB. In-vitro anti-cancer activity of Methanolic extract of leaves of Argemone Mexicana Linn.Int. J. Pharm. Tech. Res.20113313291333
    [Google Scholar]
  48. KaushikR SinghC AdlakhaM PurviaR. Therapeutic potential of Argemone maxicana L. In the perspective of ayurveda and recent research activities.2022
    [Google Scholar]
  49. Bazaldúa-RodríguezA.F. Quintanilla-LiceaR. Verde-StarM.J. Hernández-GarcíaM.E. Vargas-VillarrealJ. Garza-GonzálezJ.N. Furanocoumarins from Ruta chalepensis with amebicide activity.Molecules20212612368410.3390/molecules26123684 34208750
    [Google Scholar]
  50. Elizondo-LuevanoJ.H. Quintanilla-LiceaR. Monroy-GarcíaI.N. Assessment of anticancer properties of Argemone mexicana L. and Berberine: A comparative study.Plants20241310137410.3390/plants13101374 38794444
    [Google Scholar]
  51. Hernández-MarínD.A. Guevara-LaraF. Rivas-MoralesC. Verduzco-MartínezJ.A. Galindo-RodriguezS.A. Sánchez-GarcíaE. Biological activity of Nothoscordum bivalve (L.) britton and parthenium incanum kunth extracts.Indian J. Tradit. Knowledge 2018 Oct174699706
    [Google Scholar]
  52. RadhaA.H.M. JawadK.N. Improvement of the selectivity index (SI) and cytotoxicity activity of doxorubicin drug by panax ginseng plant extract.Arch. Razi Inst.2021763659666 34824758
    [Google Scholar]
  53. Romero-ArguellesR. Romo-SáenzC.I. Morán-SantibáñezK. In vitro antitumor activity of endophytic and rhizosphere gram-positive bacteria from Ibervillea sonorae (S. Watson) greene against L5178Y-R lymphoma cells.Int. J. Environ. Res. Public Health202219289410.3390/ijerph19020894 35055716
    [Google Scholar]
  54. Granados-EchegoyenC.A. Chan-BacabM.J. Ortega-MoralesB.O. Argemone mexicana (Papaverales: Papavaraceae) as an alternative for mosquito control: First report of larvicidal activity of flower extract.J. Med. Entomol.201956126126710.1093/jme/tjy159 30239790
    [Google Scholar]
  55. Orozco-NunnellyD.A. PruetJ. Rios-IbarraC.P. BocangelG.E.L. LefeberT. NajdeskaT. Characterizing the cytotoxic effects and several antimicrobial phytocompounds of Argemone mexicana.PLoS One2021164e024970410.1371/journal.pone.0249704 33826680
    [Google Scholar]
  56. DharmsathaphornK. McRobertsJ.A. MandelK.G. TisdaleL.D. MasuiH. A human colonic tumor cell line that maintains vectorial electrolyte transport.Am. J. Physiol.19842462 Pt 1G204G208 6141741
    [Google Scholar]
  57. BouyerP.G. TangX. WeberC.R. ShenL. TurnerJ.R. MatthewsJ.B. Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1.Am. J. Physiol. Gastrointest. Liver Physiol.20133042G142G15610.1152/ajpgi.00483.2011 23139219
    [Google Scholar]
  58. GuptaR. ChakrabartyS.K. Gibberellic acid in plant.Plant Signal. Behav.201389e2550410.4161/psb.25504 23857350
    [Google Scholar]
  59. KulshresthaS. GoelA. SiddiqiN.J. FatimaS. SharmaB. Cancer-preventive activity of Argemone mexicana linn leaves and its effect on TNF-α and NF-κB signalling.Cancers20231523565410.3390/cancers15235654 38067358
    [Google Scholar]
  60. KarinM. NF-kappaB as a critical link between inflammation and cancer.Cold Spring Harb. Perspect. Biol.200915a00014110.1101/cshperspect.a000141 20066113
    [Google Scholar]
  61. WuY. ZhouB.P. TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion.Br. J. Cancer2010102463964410.1038/sj.bjc.6605530 20087353
    [Google Scholar]
  62. XueW. MeylanE. OliverT.G. Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma.Cancer Discov.20111323624710.1158/2159‑8290.CD‑11‑0073 21874163
    [Google Scholar]
  63. KumarR. KumarR. KumariR. Novel application of traditional medicinal plants for the management and treatment of cancer.Int J Innov Sci Res Technol202271115361555
    [Google Scholar]
  64. ZhangT. MaC. ZhangZ. ZhangH. HuH. NF‐κB signaling in inflammation and cancer.MedComm20212461865310.1002/mco2.104 34977871
    [Google Scholar]
  65. SharmaA. GoelA. LinZ. In vitro and in silico anti-rheumatic arthritis activity of nyctanthes arbor-tristis.Molecules20232816612510.3390/molecules28166125 37630377
    [Google Scholar]
  66. AmiriK.I. RichmondA. Role of nuclear factor-κ B in melanoma.Cancer Metastasis Rev.200524230131310.1007/s10555‑005‑1579‑7 15986139
    [Google Scholar]
  67. KaltschmidtB. GreinerJ.F.W. KadhimH.M. KaltschmidtC. Subunit-specific role of NF-κB in cancer.Biomedicines2018624410.3390/biomedicines6020044 29673141
    [Google Scholar]
  68. VennilaG. In-vivo inhibitory potential of Argemone mexicana leaf extract on chemical induced mammary tumors in wistar rats.Afr J Biol Sci20246673017312
    [Google Scholar]
  69. ElangoG. Abdul RahumanA. KamarajC. Efficacy of medicinal plant extracts against Formosan subterranean termite, Coptotermes formosanus.Ind. Crops Prod.201236152453010.1016/j.indcrop.2011.10.032
    [Google Scholar]
  70. NayakP. KarD.M. MaharanaL. Antidiabetic activity of aerial parts of Argemone mexicana Linn. in alloxan induced hyperglycaemic rats.Pharmacologyonline20111889903
    [Google Scholar]
  71. AkueshiC.O. Antimicrobial potentials of Hyptis sauvedens Poit (Lamiaccae), Nigeria.J. Bot.2002153741
    [Google Scholar]
  72. AslanM. DeliormanO.D. OrhanN. SezikE. YesiladaE. In vivo antidiabetic and antioxidant potential of Helichrysum plicatum ssp. plicatum capitulums in streptozotocin-induced-diabetic rats.J. Ethnopharmacol.20071091545910.1016/j.jep.2006.07.001 16949229
    [Google Scholar]
  73. AslanM. OrhanD.D. OrhanN. SezikE. YeşiladaE. A study of antidiabetic and antioxidant effects of Helichrysum graveolens capitulums in streptozotocin-induced diabetic rats.J. Med. Food200710239640010.1089/jmf.2006.293 17651083
    [Google Scholar]
  74. DashG.K. SureshP. GanapatyS. Studies on hypoglycaemic and wound healing activities of Lantana camara Linn.J. Nat. Rem.200112105110
    [Google Scholar]
  75. PariL. Uma MaheswariJ. Hypoglycaemic effect of Musa sapientum L. in alloxan-induced diabetic rats.J. Ethnopharmacol.1999681-332132510.1016/S0378‑8741(99)00088‑4 10624895
    [Google Scholar]
  76. SankarS. In vitro phytochemical analysis and antioxidant activity of Argemone mexicana.Chelonian Res Found2023182872884
    [Google Scholar]
  77. KumarR. OmsatyamM.Y. Phyto-pharmacological activity and novel aspect of Lichen parmelia perlata: A review.Int J Creat Res Thoughts2023112b141b148
    [Google Scholar]
  78. SharathJ. TajR.A.S. BhagyaM. Phytochemical characterisation of Argemone mexicana leaf extracts: An evidence for its antiandrogenic and antioxidant activities.Indian J Pharm Educ Res2022562ss294s30210.5530/ijper.56.2s.100
    [Google Scholar]
  79. MumtazF. RazaS.M. AhmadZ. IftikharA. HussainM. Qualitative phytochemical analysis of some selected medicinal plants occurring in local area of Faisalabad, Pakistan.J Pharm Altern Med201433510
    [Google Scholar]
  80. IdowuO.A. SaliuO.A. FakoredeN.C. AriseR.O. Anti-ulcerogenic efficacy of leaf fractions Argemone mexicana against indomethacin-induced ulceration in rats.Asian J Emerg Res20213212913610.3923/ajerpk.2021.129.136
    [Google Scholar]
  81. HarborneJ.B. Phytochemical methods: A guide to modern techniques of plant analysis.Chapman and Hall1998
    [Google Scholar]
  82. SofoworaA. Research on medicinal plants and traditional medicine in Africa.J. Altern. Complement. Med.19962336537210.1089/acm.1996.2.365 9395671
    [Google Scholar]
  83. KumarG.S. JayaveeraK.N. A Textbook of Pharmacognosy and Phytochemistry S.Chand Publishing2014
    [Google Scholar]
  84. IdowuO.A. AriseR.O. Ameliorative and safety characteristics of Argemone mexicana in indomethacin-induced peptic ulcer.Pharmaceutical Fronts202023e133e14210.1055/s‑0040‑1722216
    [Google Scholar]
  85. AmnaO.F. NooraainH. NorihamA. AzizahA.H. HusnaR.N. Acute and oral subacute toxicity study of ethanolic extract of Cosmos caudatus leaf in Sprague Dawley rats.Int. J. Biosci. Biochem. Bioinform.201334301
    [Google Scholar]
  86. FarahmandfarR. EsmaeilzadehK.R. AsnaashariM. ShahrampourD. BakhshandehT. Bioactive compounds, antioxidant and antimicrobial activities of Arum maculatum leaves extracts as affected by various solvents and extraction methods.Food Sci. Nutr.20197246547510.1002/fsn3.815 30847124
    [Google Scholar]
  87. GahlotV. YadavD.K. Phytochemical and network pharmacology based evaluation of antiepileptic potential of identified metabolites in Argimone mexicana.Pharmacognosy Res.202113420821710.5530/pres.13.4.13
    [Google Scholar]
  88. MukherjeeP.K. RaiS. BhattacharyaS. WahileA. SahaB.P. Marker analysis of polyherbal formulation, Triphala–A well known Indian traditional medicine.Natl Inst Sci Commun Policy Res2008379383
    [Google Scholar]
  89. DwarikaP. A new 2, 8-dihydroxy-1, 6-dimethoxy xenthones from cythula tomesntosa.Orient. J. Chem.2011272765767
    [Google Scholar]
  90. SharmaA. KhannaS. KaurG. SinghI. Medicinal plants and their components for wound healing applications.Future J Pharm Sci202171113
    [Google Scholar]
  91. AyoolaG.A. CokerH.A. AdesegunS.A. Adepoju-BelloA.A. ObaweyaK. EzenniaE.C. Phytochemical screening and antioxidant activities of some selected medicinal plants used for malaria therapy in Southwestern Nigeria.Trop. J. Pharm. Res.20087310191024
    [Google Scholar]
  92. YazarluO. IranshahiM. KashaniH.R.K. Perspective on the application of medicinal plants and natural products in wound healing: A mechanistic review.Pharmacol. Res.202117410584110.1016/j.phrs.2021.105841 34419563
    [Google Scholar]
  93. VitaleS. ColaneroS. PlacidiM. Phytochemistry and biological activity of medicinal plants in wound healing: An overview of current research.Molecules20222711356610.3390/molecules27113566 35684503
    [Google Scholar]
  94. GwarzoI.D. MohdB.S.P. AbdulW.R. ZiaA. Recent advances and future prospects in topical creams from medicinal plants to expedite wound healing: A review.Biotechnol. Biotechnol. Equip.2022361829410.1080/13102818.2022.2053340
    [Google Scholar]
  95. BelachewT.F. AsradeS. GetaM. FentahunE. In vivo evaluation of wound healing and anti‐inflammatory activity of 80% methanol crude flower extract of Hagenia abyssinica (Bruce) JF Gmel in mice.Evid. Based Complement. Altern. Med.2020202019645792
    [Google Scholar]
  96. AdamS.I.Y. IdrisI.A. AbdelgadirE.H. AhmedR.H. KamalE.E. Evaluation of hepatoprotective activity of Argemone mexicana aerial part extracts on CCL_4 induced liver damage in wistar rats.Br. J. Pharmacol. Toxicol.201125251256
    [Google Scholar]
  97. ParimooH.A. SharmaR. PatilR.D. SharmaO.P. KumarP. KumarN. Hepatoprotective effect of Ginkgo biloba leaf extract on lantadenes-induced hepatotoxicity in guinea pigs.Toxicon20148111210.1016/j.toxicon.2014.01.013 24472344
    [Google Scholar]
  98. SujaS.R. LathaP.G. PushpangadanP. RajasekharanS. Evaluation of hepatoprotective effects of Helminthostachys zeylanica (L.) Hook against carbon tetrachloride-induced liver damage in Wistar rats.J. Ethnopharmacol.2004921616610.1016/j.jep.2004.01.019 15099849
    [Google Scholar]
  99. BhatS.H. ShrivastavaR. MallaM.Y. IqbalM. AnjumT. MirA.H. Hepatoprotective activity of Argemone mexicana Linn against toxic effects of carbon tetrachloride in rats.World J. Pharm. Res.20143340374048
    [Google Scholar]
  100. AgarwalM. SrivastavaV.K. SaxenaK.K. KumarA. Hepatoprotective activity of Beta vulgaris against CCl4-induced hepatic injury in rats.Fitoterapia2006772919310.1016/j.fitote.2005.11.004 16376022
    [Google Scholar]
  101. SourabiéT.S. KoneH.M. NikiémaJ.B. NacoulmaO.G. GuissouI.P. Evaluation of the antihepatotoxic effect of Argemone mexicana leaf extracts against CCl4-induced hepatic injury in rats.Int. J. Biol. Chem. Sci.20103610.4314/ijbcs.v3i6.53172
    [Google Scholar]
  102. TilakR. GangwarS.S. TilakA. ThakurR.N. SutarR.C. Screening of leaf extract of Argemone Mexicana for it’s antiasthmatic activity in isolated goat tracheal chain preparation.World J. Pharm. Res.2017
    [Google Scholar]
  103. BrekhmanI.I. DardymovI.V. New substances of plant origin which increase nonspecific resistance.Annu. Rev. Pharmacol.19699141943010.1146/annurev.pa.09.040169.002223 4892434
    [Google Scholar]
  104. ArmitageA.K. BoswoodJ. LargeB.J. Thioxanthines with potent brochodilator and coronary dilator properties.Br. J. Pharmacol. Chemother.1961161597610.1111/j.1476‑5381.1961.tb00298.x 13684289
    [Google Scholar]
  105. SharmaS. SharmaM.C. KohliD.V. Pharmacological screening effect of ethanolic and methanolic extract of fruits of medicinally leaves.Dig. J. Nanomater. Biostructures.201051229232
    [Google Scholar]
  106. KumariuS. SindhuM. SinghS. GoelN. RaniI. PanghalM. Determination of total phenolic, free radical scavenging activity and antimicrobial activity of root extracts of Argemone mexicana L. in methanol solvent.Ann. Phytomed.20221111510.54085/ap.2022.11.1.52
    [Google Scholar]
  107. BauerAW KirbyWMM SherrisJC TurckM Antibiotic susceptibility testing by a standardized single disk method.Am J Clin Pathol196645(4_ts): 493-610.1093/ajcp/45.4_ts.493 5325707
    [Google Scholar]
  108. Rivero-CruzJ.F. Granados-PinedaJ. Pedraza-ChaverriJ. Phytochemical constituents, antioxidant, cytotoxic, and antimicrobial activities of the ethanolic extract of Mexican brown propolis.Antioxidants2020917010.3390/antiox9010070 31940981
    [Google Scholar]
  109. PatelJ.B. TenoverF.C. TurnidgeJ.D. JorgensenJ.H. Susceptibility test methods: Dilution and disk diffusion methods.Man Clin Microbiol201111221143
    [Google Scholar]
  110. KoethL. MillerL. Antimicrobial Susceptibility Test Methods: Dilution and Disk Diffusion Methods.American Society of Microbiology2023119
    [Google Scholar]
  111. Torres-GonzálezA. López-RiveraP. Duarte-LisciG. López-RamírezÁ. Correa-BenítezA. Rivero-CruzJ.F. Analysis of volatile components from Melipona beecheii geopropolis from Southeast Mexico by headspace solid-phase microextraction.Nat. Prod. Res.201630223724010.1080/14786419.2015.1043631 26118891
    [Google Scholar]
  112. PiresC.A.S. Investigation of antiplasmodial compounds from various plant extracts: Argemone mexicana L. (Papaveraceae), Licania octandra (Hoffmanns. ex. Roem & Schult) Kuntze (Chrysobalanaceae) and Syzygium cumini (L.) Skeels (Myrtaceae). Doctoral Thesis2010
    [Google Scholar]
  113. ZalisM.G. PangL. SilveiraM.S. MilhousW.K. WirthD.F. Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance.Am. J. Trop. Med. Hyg.199858563063710.4269/ajtmh.1998.58.630 9598453
    [Google Scholar]
  114. VarshneyP. DashS.K. BhatiaA.K. In vitro and in vivo antiviral potential of hot aqueous extract of ocimum sanctum and Argemone mexicana leaves.Med Plant Res2013311788610.5376/mpr.2013.03.0011
    [Google Scholar]
  115. GoelA. SinghR. DashS. GuptaD. PillaiA. YadavS.K. Antiviral activity of few selected indigenous plants against bovine herpes Virus-1.J Immunol Immunopathol20111313037
    [Google Scholar]
  116. CapassoA. PiacenteS. PizzaC. De TommasiN. JativaC. SorrentinoL. Isoquinoline alkaloids from Argemone mexicana reduce morphine withdrawal in guinea pig isolated ileum.Planta Med.199763432632810.1055/s‑2006‑957693 9270378
    [Google Scholar]
  117. IbrahimH.A. IbrahimH. Phytochemical screening and toxicity evaluation on the leaves of Argemone mexicana Linn.(Papaveraceae).Int J Appl Sci200933943
    [Google Scholar]
  118. VermaS.K. DevG. TyagiA.K. GoomberS. JainG.V. Argemone mexicana poisoning: Autopsy findings of two cases.Forensic Sci. Int.20011151-213514110.1016/S0379‑0738(00)00322‑4 11056284
    [Google Scholar]
  119. HusainS. NarsimhaR. RaoR.N. Separation, identification and determination of sanguinarine in argemone and other adulterated edible oils by reversed-phase high-performance liquid chromatography.J. Chromatogr. A1999863112312610.1016/S0021‑9673(99)00964‑4 10591470
    [Google Scholar]
  120. DalviR.R. Sanguinarine: its potential, as a liver toxic alkaloid present in the seeds of Argemone mexicana.Experientia1985411777810.1007/BF02005884 3967743
    [Google Scholar]
  121. SoodN.N. SachdevM.S. MohanM. GuptaS.K. SachdevH.P.S. Epidemic dropsy following transcutaneous absorption of Argemone mexicana oil.Trans. R. Soc. Trop. Med. Hyg.198579451051210.1016/0035‑9203(85)90079‑3 4082260
    [Google Scholar]
  122. DeroussentA. RéM. HoellingerH. CresteilT. Metabolism of sanguinarine in human and in rat: Characterization of oxidative metabolites produced by human CYP1A1 and CYP1A2 and rat liver microsomes using liquid chromatography–tandem mass spectrometry.J. Pharm. Biomed. Anal.201052339139710.1016/j.jpba.2009.09.014 19804952
    [Google Scholar]
  123. AnsariK.M. ChauhanL.K.S. DhawanA. KhannaS.K. DasM. Unequivocal evidence of genotoxic potential of argemone oil in mice.Int. J. Cancer2004112589089510.1002/ijc.20319 15386392
    [Google Scholar]
  124. UpretiK.K. DasM. KumarA. SinghG.B. KhannaS.K. Biochemical toxicology of argemone oil. IV short-term oral feeding response in rats.Toxicology198958328529810.1016/0300‑483X(89)90142‑X 2799830
    [Google Scholar]
  125. FifieldF.W. Principles and practice of analytical chemistry.Wiley2000
    [Google Scholar]
  126. KaurK.K. AllahbadiaG. SinghM. Synthesis and functional significance of poly unsaturated fatty acids (PUFA’s) in body.Acta Sci Nutr Heal2018248
    [Google Scholar]
  127. SainiR.K. PrasadP. SreedharR.V. Akhilender NaiduK. ShangX. KeumY.S. Omega-3 polyunsaturated fatty acids (PUFAs): Emerging plant and microbial sources, oxidative stability, bioavailability, and health benefits-A review.Antioxidants20211010162710.3390/antiox10101627 34679761
    [Google Scholar]
  128. VermaS. Phytochemical and pharmacological study on Argemone mexicana Linn (Papaveraceae).Int. J. Pharm.2017719093
    [Google Scholar]
  129. MuinatA.A. MbangF.O.N. LateefB.G. TemionuE.O. OluyemisiB.A. Antimicrobial studies of the leaf extract of Argemone mexicana and its ointment formulation.W Afr J Pharm20152613340
    [Google Scholar]
  130. FebriyentiF. FitriaN. MohtarN. UmarS. NovizaD. RineldiS. Honey gel and film for burn wound.Int. J. Drug Deliv.20146
    [Google Scholar]
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