Skip to content
2000
image of Phytochemical and Phytopharmacological Insights into Argemonemexicana: Integrative Approaches in Eastern Indian Region as Folk Medicine

Abstract

Introduction

, commonly known as the Mexican poppy, has earned significant recognition in the traditional healing systems of the Eastern Indian region, where it has been used for centuries as a folk remedy for a variety of diseases. The study was based on search or identified through Pubmed, Google Scholar, Science Direct, .

Meta-analysis

Phytochemical analysis has demonstrated that the alkaloids present in exhibit potent antimicrobial properties, making the plant an effective natural remedy for treating infections caused by bacteria, fungi, and viruses. In addition, the plant’s flavonoids and phenolic compounds are recognized for their strong anti-inflammatory and antioxidant activities, which play a crucial role in alleviating pain, reducing inflammation, and promoting tissue repair. Furthermore, has shown significant analgesic effects, which support its traditional use as a pain reliever. The integration of ethnobotanical knowledge with modern pharmacological research is essential for fully unlocking the therapeutic potential of .

Future Scope

Future studies must focus on comprehensive clinical trials, toxicological evaluations, and in-depth mechanistic investigations to validate the efficacy and safety of in human populations.

Conclusion

This review highlights the urgent need for further research to bridge the gap between traditional knowledge and contemporary scientific understanding. By advancing the study of , there is a significant opportunity to develop novel, cost-effective, and sustainable therapeutic agents that could serve as alternatives to synthetic drugs, particularly in regions where access to modern healthcare is limited.

© 2025 Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/cdrr/10.2174/0125899775362872250319082142
2025-04-04
2025-08-13

  • From This Site

    /content/journals/cdrr/10.2174/0125899775362872250319082142
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. Humans IWG on the E of CR to Cancer IA for R on, Organization WH. Some traditional herbal medicines, some mycotoxins, naphthalene and styrene. World Health Organization 2002
    [Google Scholar]
  2. Blumenthal M. The german commission e monograph system for phytomedicines: A model for regulatory reform in the United States. Phytomedicines of Europe ACS Symposium Series American Chemical Society 1998 691 30 36 10.1021/bk‑1998‑0691.ch003
    [Google Scholar]
  3. Organization W.H. WHO monographs on selected medicinal plants. World Health Organization 1999 2
    [Google Scholar]
  4. Gregory P. Jellin J. Batz F. The natural medicines comprehensive database. Pharm. Lett. 2013
    [Google Scholar]
  5. Tag H. Das A.K. Loyi H. Anti-inflammatory plants used by the Khamti tribe of Lohit district in eastern Arunachal Pradesh, India. Nat. Prod. Radiance 2007 6 334 340
    [Google Scholar]
  6. Mukherjee P.K. Bahadur S. Harwansh R.K. Biswas S. Banerjee S. Paradigm shift in natural product research: Traditional medicine inspired approaches. Phytochem. Rev. 2017 16 5 803 826 10.1007/s11101‑016‑9489‑6
    [Google Scholar]
  7. Alam A Khan A. Argemone mexicana L.: A weed with versatile medicinal and pharmacological applications. Ann. Phytomed. 2020 9
    [Google Scholar]
  8. Joshi N. Bhatt S. Dhyani D. Nain J. Phytochemical screening of secondary metabolites of Argemone mexicana Linn. Flowers. Int. J. Curr. Pharm. Res. 2013 5 144 147
    [Google Scholar]
  9. Malik C. Priya Mohanty J. Pradhan S. Sharma C. Phytochemistry and pharmacology of Argemone mexicana Linn – An Indian medicinal plant. Res J Pharmacol Phytochem. 2023 15 1 27 32 10.52711/0975‑4385.2023.00005
    [Google Scholar]
  10. Pathak R. Medicinal property and ethnopharmacological activities of Argemone mexicana: An overview. Ann. Rom. Soc. Cell Biol. 2021 25 3 1615 1641
    [Google Scholar]
  11. Patocka J. Ovando-Martínez M. Navratilova Z. Oleksak P. Ogwu M.C. Nepovimova E. Kuca K. Argemone mexicana L. (Papaveraceae): Chemistry, pharmacology, and toxicology. Phytochem. Rev. 2024 23 4 1167 1182 10.1007/s11101‑024‑09918‑y
    [Google Scholar]
  12. Sharanappa R. Ant profile, phytochemistry and pharmacology of Argemone mexicana linn. A review. Int. J. Pharm. Pharm. Sci. 2014 6 7 46 53
    [Google Scholar]
  13. Siddiqui I.A. Shaukat S.S. Khan G.H. Zaki M.J. Evaluation of Argemone mexicana for control of root‐infecting fungi in tomato. J. Phytopathol. 2002 150 6 321 329 10.1046/j.1439‑0434.2002.00762.x
    [Google Scholar]
  14. Mariod A.A. Saeed Mirghani M.E. Hussein I. Chapter 2 - Argemone mexicana (Argemone Seed). Unconventional Oilseeds and Oil Sources Academic Press 2017 9 12
    [Google Scholar]
  15. Thorat V.H. Ghorpade S. Argemone mexicana Linn. having medicinal property. Int. J. Pharmacogn. 2018 5 2 82 90
    [Google Scholar]
  16. Israilov I.A. Yunusov M.S. Alkaloids of four species of Argemone. Chem. Nat. Compd. 1986 22 2 189 192 10.1007/BF00574736
    [Google Scholar]
  17. Santos A.C. Adkilen P. The alkaloids of Argemone mexicana. J. Am. Chem. Soc. 1932 54 7 2923 2924 10.1021/ja01346a037
    [Google Scholar]
  18. Haisová K. Slavík J. On the minor alkaloids from Argemone mexicana L. Collect. Czech. Chem. Commun. 1975 40 5 1576 1578 10.1135/cccc19751576
    [Google Scholar]
  19. Chang Y.C. Chang F.R. Khalil A.T. Hsieh P.W. Wu Y.C. Cytotoxic benzophenanthridine and benzylisoquinoline alkaloids from Argemone mexicana. Z. Naturforsch. C J. Biosci. 2003 58 7-8 521 526 10.1515/znc‑2003‑7‑813 12939038
    [Google Scholar]
  20. Bentley K.W. β-Phenylethylamines and the isoquinoline alkaloids (July 1999 to June 2000). Nat. Prod. Rep. 2001 18 2 148 170 10.1039/a909672h 11336286
    [Google Scholar]
  21. Bhattacharjee I. Chatterjee S.K. Chatterjee S. Chandra G. Antibacterial potentiality of Argemone mexicana solvent extracts against some pathogenic bacteria. Mem. Inst. Oswaldo Cruz 2006 101 6 645 648 10.1590/S0074‑02762006000600011 17072477
    [Google Scholar]
  22. Chang Y.C. Hsieh P.W. Chang F.R. Wu R.R. Liaw C.C. Lee K.H. Wu Y.C. Two new protopines argemexicaines A and B and the anti-HIV alkaloid 6-acetonyldihydrochelerythrine from formosan Argemone mexicana. Planta Med. 2003 69 2 148 152 10.1055/s‑2003‑37710 12624820
    [Google Scholar]
  23. Singh S. Singh A. Jaiswal J. Singh T.D. Singh V.P. Pandey V.B. Tiwari A. Singh U.P. Antifungal activity of the mixture of quaternary alkaloids isolated from Argemone mexicana against some phytopathogenic fungi. Arch. Phytopathol. Pflanzenschutz 2010 43 8 769 774 10.1080/03235400802176159
    [Google Scholar]
  24. Singh A. Singh S. Singh S. Singh T. Singh V. Pandey V. Singh U. Fungal spore germination inhibition by alkaloids dehydrocorydalmine and oxyberberine. J. Plant Prot. Res. 2009 49 3 49 10.2478/v10045‑009‑0046‑9
    [Google Scholar]
  25. Gupta R.S. Dixit V.P. Dobhal M.P. Antifertility studies of isoquinoline alkaloids with special emphasis on structure activity relationship. Fitoterapia 1990 61 1 67 71
    [Google Scholar]
  26. Shamma M. The isoquinoline alkaloids chemistry and pharmacology. Elsevier 2012 25
    [Google Scholar]
  27. Nakkady S. Shamma M. Studies on the chemical constitution of Argemone mexicana. Egypt. J. Pharm. Sci. 1988 29 1–4 53 61
    [Google Scholar]
  28. Tripathi P.N. Alkaloids of Argemone Mexican A. Orient. J. Chem. 1999 15 1
    [Google Scholar]
  29. Fletcher M.T. Takken G. Blaney B.J. Alberts V. Isoquinoline alkaloids and keto-fatty acids of Argemone ochroleuca and A. mexicana (mexican poppy) seed. I. An assay method and factors affecting their concentration. Aust. J. Agric. Res. 1993 44 2 265 275 10.1071/AR9930265
    [Google Scholar]
  30. Hussain S.F. Nakkady S. Khan L. Shamma M. Oxyhydrastinine, an isoquinolone alkaloid from the papaveraceae. Phytochemistry 1983 22 1 319 320 10.1016/S0031‑9422(00)80125‑9
    [Google Scholar]
  31. Rahman A. Ahmad V.U. Handbook of Natural Products Data: Isoquinoline alkaloids Elsevier 1990
    [Google Scholar]
  32. Sukumar D. Nambi R.A.S.N. Studies on the leaves of Agremonemexicana. Fitoterapia 1984 55 325 353
    [Google Scholar]
  33. Bose B.C. Vijayvargiya R. Saifi A.Q. Sharma S.K. Chemical and pharmacological studies on Argemone mexicana. J. Pharm. Sci. 1963 52 12 1172 1175 10.1002/jps.2600521216 14088969
    [Google Scholar]
  34. Yadav R.N.S. Agarwala M. Phytochemical analysis of some medicinal plants. J. Phytol. 2011 3 12
    [Google Scholar]
  35. Harborne J.B. Williams C.A. Flavonoids in the seeds of Argemone mexicana: A reappraisal. Phytochemistry 1983 22 6 1520 1521 10.1016/S0031‑9422(00)84057‑1
    [Google Scholar]
  36. Rahman W. Ilyas M. Flower Pigments. Flavonoids from Argemone mexicana linn. (Papaveraceae). J. Org. Chem. 1962 27 1 153 155 10.1021/jo01048a037
    [Google Scholar]
  37. Singh S. Singh T. Pandey V.B. Constituents of Argemone species. J. Indian Chem. Soc. 2011 88 275 276
    [Google Scholar]
  38. Singh S. Pandey V.B. Singh T.D. Alkaloids and flavonoids of Argemone mexicana. Nat. Prod. Res. 2012 26 1 16 21 10.1080/14786419.2010.529809 21722040
    [Google Scholar]
  39. Bhardwaj D.K. Bisht M.S. Jain R.K. Munjal A. Phenolics from the seeds of Argemone mexicana. Phytochemistry 1982 21 8 2154 2156 10.1016/0031‑9422(82)83078‑1
    [Google Scholar]
  40. Dwivedi D.S. Dwivedi D. Kapadia R. Argemone Mexicana Linn. (Ghamoya) : A weed having great therapeutic values in folk remedies. Pharm. Rev. 2008
    [Google Scholar]
  41. Badami R.C. Gunstone F.D. Vegetable oils. X.—Examination of component acids of Argemone mexicana seed oil by reversed‐phase chromatography. J. Sci. Food Agric. 1962 13 4 255 257 10.1002/jsfa.2740130407
    [Google Scholar]
  42. PLANT AMAHM ARGEMONE MEXICANA A HIDDEN MEDICINAL PLANT AND TO EVALUATE ITS EDIBILITY. Drugs 1 2
    [Google Scholar]
  43. Brahmachari G. Gorai D. Roy R. Argemone mexicana: Chemical and pharmacological aspects. Rev. Bras. Farmacogn. 2013 23 3 559 575 10.1590/S0102‑695X2013005000021
    [Google Scholar]
  44. Singh R. Chaubey N. Mishra R.K. Evaluation of anti-asthmatic activity of ethanolic extract of Argemone mexicana stems. Saudi J Med Pharm Sci. 2021 7 1 39 44 10.36348/sjmps.2021.v07i01.007
    [Google Scholar]
  45. Pawar R.J. Govilkar S.A. Ahire S.B. Bairagi V.A.A. Review: Argemone mexicana is an indigenous herb. Int. J. Pharmacogn. 2020 7 6 137 143
    [Google Scholar]
  46. Varun S Sellappa S In vitro screening of phytochemicals and anticancer activity of Argemone Mexicana leaf extract. World J. Pharm. Res. 2014 3 8 547 556
    [Google Scholar]
  47. Gali Kiranmayi GK Ramakrishnan G Kothai R Jaykar B In-vitro anti-cancer activity of Methanolic extract of leaves of Argemone Mexicana Linn. Int. J. PharmTech Res. 2011 3 3 1329 1333
    [Google Scholar]
  48. Kaushik R Singh C Adlakha M Purvia R. Therapeutic potential of Argemone maxicana L. In the perspective of ayurveda and recent research activities. 2022
    [Google Scholar]
  49. Bazaldúa-Rodríguez A.F. Quintanilla-Licea R. Verde-Star M.J. Hernández-García M.E. Vargas-Villarreal J. Garza-González J.N. Furanocoumarins from Ruta chalepensis with amebicide activity. Molecules 2021 26 12 3684 10.3390/molecules26123684 34208750
    [Google Scholar]
  50. Elizondo-Luevano J.H. Quintanilla-Licea R. Monroy-García I.N. Kačániová M. Castillo-Velázquez U. Bazaldúa-Rodríguez A.F. Garza-Vega L.M. Torres-Hernández Á.D. Chávez-Montes A. Assessment of anticancer properties of Argemone mexicana L. and Berberine: A comparative study. Plants 2024 13 10 1374 10.3390/plants13101374 38794444
    [Google Scholar]
  51. Hernández-Marín DA Guevara-Lara F Rivas-Morales C Verduzco-Martínez JA Galindo-Rodriguez SA Sánchez-García E Biological activity of Nothoscordum bivalve (L.) britton and parthenium incanum kunth extracts. Indian J. Tradit. Knowledge 2018 Oct 17 4 699 706
    [Google Scholar]
  52. Radha Abbas Hasoon M. Jawad Kadhim N. Improvement of the selectivity index (SI) and cytotoxicity activity of doxorubicin drug by panax ginseng plant extract. Arch. Razi Inst. 2021 76 3 659 666 34824758
    [Google Scholar]
  53. Romero-Arguelles R. Romo-Sáenz C.I. Morán-Santibáñez K. Tamez-Guerra P. Quintanilla-Licea R. Orozco-Flores A.A. Ramírez-Villalobos J.M. Tamez-Guerra R. Rodríguez-Padilla C. Gomez-Flores R. In vitro antitumor activity of endophytic and rhizosphere gram-positive bacteria from Ibervillea sonorae (S. Watson) greene against L5178Y-R lymphoma cells. Int. J. Environ. Res. Public Health 2022 19 2 894 10.3390/ijerph19020894 35055716
    [Google Scholar]
  54. Granados-Echegoyen C.A. Chan-Bacab M.J. Ortega-Morales B.O. Vásquez-López A. Lagunez-Rivera L. Diego-Nava F. Gaylarde C. Argemone mexicana (Papaverales: Papavaraceae) as an alternative for mosquito control: First report of larvicidal activity of flower extract. J. Med. Entomol. 2019 56 1 261 267 10.1093/jme/tjy159 30239790
    [Google Scholar]
  55. Orozco-Nunnelly D.A. Pruet J. Rios-Ibarra C.P. Bocangel Gamarra E.L. Lefeber T. Najdeska T. Characterizing the cytotoxic effects and several antimicrobial phytocompounds of Argemone mexicana. PLoS One 2021 16 4 e0249704 10.1371/journal.pone.0249704 33826680
    [Google Scholar]
  56. Dharmsathaphorn K. McRoberts J.A. Mandel K.G. Tisdale L.D. Masui H. A human colonic tumor cell line that maintains vectorial electrolyte transport. Am. J. Physiol. 1984 246 2 Pt 1 G204 G208 6141741
    [Google Scholar]
  57. Bouyer P.G. Tang X. Weber C.R. Shen L. Turner J.R. Matthews J.B. Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. Am. J. Physiol. Gastrointest. Liver Physiol. 2013 304 2 G142 G156 10.1152/ajpgi.00483.2011 23139219
    [Google Scholar]
  58. Gupta R. Chakrabarty S.K. Gibberellic acid in plant. Plant Signal. Behav. 2013 8 9 e25504 10.4161/psb.25504 23857350
    [Google Scholar]
  59. Kulshrestha S. Goel A. Siddiqi N.J. Fatima S. Sharma B. Cancer-preventive activity of Argemone mexicana linn leaves and its effect on TNF-α and NF-κB signalling. Cancers 2023 15 23 5654 10.3390/cancers15235654 38067358
    [Google Scholar]
  60. Karin M. NF-kappaB as a critical link between inflammation and cancer. Cold Spring Harb. Perspect. Biol. 2009 1 5 a000141 10.1101/cshperspect.a000141 20066113
    [Google Scholar]
  61. Wu Y. Zhou B.P. TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion. Br. J. Cancer 2010 102 4 639 644 10.1038/sj.bjc.6605530 20087353
    [Google Scholar]
  62. Xue W. Meylan E. Oliver T.G. Feldser D.M. Winslow M.M. Bronson R. Jacks T. Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma. Cancer Discov. 2011 1 3 236 247 10.1158/2159‑8290.CD‑11‑0073 21874163
    [Google Scholar]
  63. Kumar R. Kumar R. Kumari R. Novel application of traditional medicinal plants for the management and treatment of cancer. Int J Innov Sci Res Technol 2022 7 11 1536 1555
    [Google Scholar]
  64. Zhang T. Ma C. Zhang Z. Zhang H. Hu H. NF‐κB signaling in inflammation and cancer. MedComm 2021 2 4 618 653 10.1002/mco2.104 34977871
    [Google Scholar]
  65. Sharma A. Goel A. Lin Z. In vitro and in silico anti-rheumatic arthritis activity of nyctanthes arbor-tristis. Molecules 2023 28 16 6125 10.3390/molecules28166125 37630377
    [Google Scholar]
  66. Amiri K.I. Richmond A. Role of nuclear factor-κ B in melanoma. Cancer Metastasis Rev. 2005 24 2 301 313 10.1007/s10555‑005‑1579‑7 15986139
    [Google Scholar]
  67. Kaltschmidt B. Greiner J.F.W. Kadhim H.M. Kaltschmidt C. Subunit-specific role of NF-κB in cancer. Biomedicines 2018 6 2 44 10.3390/biomedicines6020044 29673141
    [Google Scholar]
  68. Vennila G. In-vivo inhibitory potential of Argemone mexicana leaf extract on chemical induced mammary tumors in wistar rats. Afr. J. Biol. Sci. 2024 6 6 7301 7312
    [Google Scholar]
  69. Elango G. Abdul Rahuman A. Kamaraj C. Bagavan A. Abduz Zahir A. Santhoshkumar T. Marimuthu S. Velayutham K. Jayaseelan C. Kirthi A.V. Rajakumar G. Efficacy of medicinal plant extracts against Formosan subterranean termite, Coptotermes formosanus. Ind. Crops Prod. 2012 36 1 524 530 10.1016/j.indcrop.2011.10.032
    [Google Scholar]
  70. Nayak P. Kar D.M. Maharana L. Antidiabetic activity of aerial parts of Argemone mexicana Linn. in alloxan induced hyperglycaemic rats. Pharmacologyonline 2011 1 889 903
    [Google Scholar]
  71. Akueshi C.O. Antimicrobial potentials of Hyptis sauvedens Poit (Lamiaccae), Nigeria. J. Bot. 2002 15 37 41
    [Google Scholar]
  72. Aslan M. Deliorman Orhan D. Orhan N. Sezik E. Yesilada E. In vivo antidiabetic and antioxidant potential of Helichrysum plicatum ssp. plicatum capitulums in streptozotocin-induced-diabetic rats. J. Ethnopharmacol. 2007 109 1 54 59 10.1016/j.jep.2006.07.001 16949229
    [Google Scholar]
  73. Aslan M. Orhan D.D. Orhan N. Sezik E. Yeşilada E. A study of antidiabetic and antioxidant effects of Helichrysum graveolens capitulums in streptozotocin-induced diabetic rats. J. Med. Food 2007 10 2 396 400 10.1089/jmf.2006.293 17651083
    [Google Scholar]
  74. Dash G.K. Suresh P. Ganapaty S. Studies on hypoglycaemic and wound healing activities of Lantana camara Linn. J. Nat. Rem. 2001 1 2 105 110
    [Google Scholar]
  75. Pari L. Uma Maheswari J. Hypoglycaemic effect of Musa sapientum L. in alloxan-induced diabetic rats. J. Ethnopharmacol. 1999 68 1-3 321 325 10.1016/S0378‑8741(99)00088‑4 10624895
    [Google Scholar]
  76. Sankar S. Invitro phytochemical analysis and antioxidant activity of Argemone mexicana. Chelonian Res. Found. 2023 18 2 872 884
    [Google Scholar]
  77. Kumar R. Omsatyam M.Y. Phyto-pharmacological activity and novel aspect of Lichen parmelia perlata: A review. Int J Creat Res Thoughts 2023 11 2 b141 b148
    [Google Scholar]
  78. Sharath J. Taj R.A.S. Bhagya M. Phytochemical characterisation of Argemone mexicana leaf extracts: An evidence for its antiandrogenic and antioxidant activities. Indian J Pharm Educ Res. 2022 56 2s s294 s302 10.5530/ijper.56.2s.100
    [Google Scholar]
  79. Mumtaz F. Raza S.M. Ahmad Z. Iftikhar A. Hussain M. Qualitative phytochemical analysis of some selected medicinal plants occurring in local area of Faisalabad, Pakistan. J Pharm Altern Med. 2014 3 3 5 10
    [Google Scholar]
  80. Idowu O.A. Saliu O.A. Fakorede N.C. Arise R.O. Anti-ulcerogenic efficacy of leaf fractions Argemone mexicana against indomethacin-induced ulceration in rats. Asian J Emerg Res. 2021 3 2 129 136 10.3923/ajerpk.2021.129.136
    [Google Scholar]
  81. Harborne J.B. Phytochemical methods: A guide to modern techniques of plant analysis. Chapman and Hall 1998
    [Google Scholar]
  82. Sofowora A. Research on medicinal plants and traditional medicine in Africa. J. Altern. Complement. Med. 1996 2 3 365 372 10.1089/acm.1996.2.365 9395671
    [Google Scholar]
  83. Kumar G.S. Jayaveera K.N. A Textbook of Pharmacognosy and Phytochemistry. S. Chand Publishing 2014
    [Google Scholar]
  84. Idowu O.A. Arise R.O. Ameliorative and safety characteristics of Argemone mexicana in indomethacin-induced peptic ulcer. Pharmaceutical Fronts 2020 2 3 e133 e142 10.1055/s‑0040‑1722216
    [Google Scholar]
  85. Amna O.F. Nooraain H. Noriham A. Azizah A.H. Husna R.N. Acute and oral subacute toxicity study of ethanolic extract of Cosmos caudatus leaf in Sprague Dawley rats. Int. J. Biosci. Biochem. Bioinform. 2013 3 4 301
    [Google Scholar]
  86. Farahmandfar R. Esmaeilzadeh Kenari R. Asnaashari M. Shahrampour D. Bakhshandeh T. Bioactive compounds, antioxidant and antimicrobial activities of Arum maculatum leaves extracts as affected by various solvents and extraction methods. Food Sci. Nutr. 2019 7 2 465 475 10.1002/fsn3.815 30847124
    [Google Scholar]
  87. Gahlot V. Yadav D.K. Phytochemical and network pharmacology based evaluation of antiepileptic potential of identified metabolites in argimone mexicana. Pharmacognosy Res. 2021 13 4 208 217 10.5530/pres.13.4.13
    [Google Scholar]
  88. Mukherjee P.K. Rai S. Bhattacharya S. Wahile A. Saha B.P. Marker analysis of polyherbal formulation, Triphala–A well known Indian traditional medicine. Natl. Inst. Sci. Commun. Policy Res. 2008 379 383
    [Google Scholar]
  89. Dwarika P. A new 2, 8-dihydroxy-1, 6-dimethoxy xenthones from cythula tomesntosa. Orient. J. Chem. 2011 27 2 765 767
    [Google Scholar]
  90. Sharma A. Khanna S. Kaur G. Singh I. Medicinal plants and their components for wound healing applications. Future J. Pharm. Sci. 2021 7 1 1 13
    [Google Scholar]
  91. Ayoola G.A. Coker H.A. Adesegun S.A. Adepoju-Bello A.A. Obaweya K. Ezennia E.C. Phytochemical screening and antioxidant activities of some selected medicinal plants used for malaria therapy in Southwestern Nigeria. Trop. J. Pharm. Res. 2008 7 3 1019 1024
    [Google Scholar]
  92. Yazarlu O. Iranshahi M. Kashani H.R.K. Reshadat S. Habtemariam S. Iranshahy M. Hasanpour M. Perspective on the application of medicinal plants and natural products in wound healing: A mechanistic review. Pharmacol. Res. 2021 174 105841 10.1016/j.phrs.2021.105841 34419563
    [Google Scholar]
  93. Vitale S. Colanero S. Placidi M. Di Emidio G. Tatone C. Amicarelli F. D’Alessandro A.M. Phytochemistry and biological activity of medicinal plants in wound healing: An overview of current research. Molecules 2022 27 11 3566 10.3390/molecules27113566 35684503
    [Google Scholar]
  94. Gwarzo I.D. Mohd Bohari S.P. Abdul Wahab R. Zia A. Recent advances and future prospects in topical creams from medicinal plants to expedite wound healing: A review. Biotechnol. Biotechnol. Equip. 2022 36 1 82 94 10.1080/13102818.2022.2053340
    [Google Scholar]
  95. Belachew T.F. Asrade S. Geta M. Fentahun E. In vivo evaluation of wound healing and anti‐inflammatory activity of 80% methanol crude flower extract of Hagenia abyssinica (Bruce) JF Gmel in mice. Evid. Based Complement Altern. Med. 2020 2020 1 9645792
    [Google Scholar]
  96. Adam S.I.Y. Idris I.A. Abdelgadir E.H. Ahmed R.H. Kamal E.E. Evaluation of hepatoprotective activity of Argemone mexicana aerial part extracts on CCL_4 induced liver damage in wistar rats. Br. J. Pharmacol. Toxicol. 2011 2 5 251 256
    [Google Scholar]
  97. Parimoo H.A. Sharma R. Patil R.D. Sharma O.P. Kumar P. Kumar N. Hepatoprotective effect of Ginkgo biloba leaf extract on lantadenes-induced hepatotoxicity in guinea pigs. Toxicon 2014 81 1 12 10.1016/j.toxicon.2014.01.013 24472344
    [Google Scholar]
  98. Suja S.R. Latha P.G. Pushpangadan P. Rajasekharan S. Evaluation of hepatoprotective effects of Helminthostachys zeylanica (L.) Hook against carbon tetrachloride-induced liver damage in Wistar rats. J. Ethnopharmacol. 2004 92 1 61 66 10.1016/j.jep.2004.01.019 15099849
    [Google Scholar]
  99. Bhat S.H. Shrivastava R. Malla M.Y. Iqbal M. Anjum T. Mir A.H. Hepatoprotective activity of Argemone mexicana Linn against toxic effects of carbon tetrachloride in rats. World J. Pharm. Res. 2014 3 3 4037 4048
    [Google Scholar]
  100. Agarwal M. Srivastava V.K. Saxena K.K. Kumar A. Hepatoprotective activity of Beta vulgaris against CCl4-induced hepatic injury in rats. Fitoterapia 2006 77 2 91 93 10.1016/j.fitote.2005.11.004 16376022
    [Google Scholar]
  101. Sourabié T.S. Kone H.M. Nikiéma J.B. Nacoulma O.G. Guissou I.P. Evaluation of the antihepatotoxic effect of Argemone mexicana leaf extracts against CCl4-induced hepatic injury in rats. Int. J. Biol. Chem. Sci. 2010 3 6 10.4314/ijbcs.v3i6.53172
    [Google Scholar]
  102. Tilak R Gangwar SS Tilak A Thakur RN Sutar RC Screening of leaf extract of Argemone Mexicana for it’s antiasthmatic activity in isolated goat tracheal chain preparation. World J Pharm Res. 2017
    [Google Scholar]
  103. Brekhman I.I. Dardymov I.V. New substances of plant origin which increase nonspecific resistance. Annu. Rev. Pharmacol. 1969 9 1 419 430 10.1146/annurev.pa.09.040169.002223 4892434
    [Google Scholar]
  104. Armitage A.K. Boswood J. Large B.J. Thioxanthines with potent brochodilator and coronary dilator properties. Br. J. Pharmacol. Chemother. 1961 16 1 59 76 10.1111/j.1476‑5381.1961.tb00298.x 13684289
    [Google Scholar]
  105. Sharma S Sharma MC Kohli D V Pharmacological screening effect of ethanolic and methanolic extract of fruits of medicinally leaves. Dig. J. Nanomater. Biostructures 2010 5 1 229 232
    [Google Scholar]
  106. Kumariu S. Sindhu M. Singh S. Goel N. Rani I. Panghal M. Determination of total phenolic, free radical scavenging activity and antimicrobial activity of root extracts of Argemone mexicana L. in methanol solvent. Ann. Phytomed. 2022 11 1 1 5 10.54085/ap.2022.11.1.52
    [Google Scholar]
  107. Bauer A.W. Kirby W.M.M. Sherris J.C. Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol. 1966 45 4_ts 493 496 10.1093/ajcp/45.4_ts.493 5325707
    [Google Scholar]
  108. Rivero-Cruz J.F. Granados-Pineda J. Pedraza-Chaverri J. Pérez-Rojas J.M. Kumar-Passari A. Diaz-Ruiz G. Rivero-Cruz B.E. Phytochemical constituents, antioxidant, cytotoxic, and antimicrobial activities of the ethanolic extract of Mexican brown propolis. Antioxidants 2020 9 1 70 10.3390/antiox9010070 31940981
    [Google Scholar]
  109. Patel J.B. Tenover F.C. Turnidge J.D. Jorgensen J.H. Susceptibility test methods: Dilution and disk diffusion methods. Man. Clin. Microbiol. 2011 1122 1143
    [Google Scholar]
  110. Koeth L. Miller L. Antimicrobial Susceptibility Test Methods: Dilution and Disk Diffusion Methods American Society of Microbiology 2023 1 19
    [Google Scholar]
  111. Torres-González A. López-Rivera P. Duarte-Lisci G. López-Ramírez Á. Correa-Benítez A. Rivero-Cruz J.F. Analysis of volatile components from Melipona beecheii geopropolis from Southeast Mexico by headspace solid-phase microextraction. Nat. Prod. Res. 2016 30 2 237 240 10.1080/14786419.2015.1043631 26118891
    [Google Scholar]
  112. Pires CAS Investigation of antiplasmodial compounds from various plant extracts: Argemone mexicana L.(Papaveraceae), Licania octandra (Hoffmanns. ex. Roem & Schult) Kuntze (Chrysobalanaceae) and Syzygium cumini (L.) Skeels (Myrtaceae). Doctoral Thesis 2010
    [Google Scholar]
  113. Zalis M.G. Pang L. Silveira M.S. Milhous W.K. Wirth D.F. Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance. Am. J. Trop. Med. Hyg. 1998 58 5 630 637 10.4269/ajtmh.1998.58.630 9598453
    [Google Scholar]
  114. Varshney P. Dash S.K. Bhatia A.K. In vitro and in vivo antiviral potential of hot aqueous extract of ocimum sanctum and Argemone mexicana leaves. Med. Plant Res. 2013 3 11 78 86 10.5376/mpr.2013.03.0011
    [Google Scholar]
  115. Goel A. Singh R. Dash S. Gupta D. Pillai A. Yadav S.K. Antiviral activity of few selected indigenous plants against bovine herpes Virus-1. J Immunol Immunopathol. 2011 13 1 30 37
    [Google Scholar]
  116. Capasso A. Piacente S. Pizza C. De Tommasi N. Jativa C. Sorrentino L. Isoquinoline alkaloids from Argemone mexicana reduce morphine withdrawal in guinea pig isolated ileum. Planta Med. 1997 63 4 326 328 10.1055/s‑2006‑957693 9270378
    [Google Scholar]
  117. Ibrahim H.A. Ibrahim H. Phytochemical screening and toxicity evaluation on the leaves of Argemone mexicana Linn.(Papaveraceae). Int J Appl Sci. 2009 3 39 43
    [Google Scholar]
  118. Verma S.K. Dev G. Tyagi A.K. Goomber S. Jain G.V. Argemone mexicana poisoning: Autopsy findings of two cases. Forensic Sci. Int. 2001 115 1-2 135 141 10.1016/S0379‑0738(00)00322‑4 11056284
    [Google Scholar]
  119. Husain S. Narsimha R. Rao R.N. Separation, identification and determination of sanguinarine in argemone and other adulterated edible oils by reversed-phase high-performance liquid chromatography. J. Chromatogr. A 1999 863 1 123 126 10.1016/S0021‑9673(99)00964‑4 10591470
    [Google Scholar]
  120. Dalvi R.R. Sanguinarine: its potential, as a liver toxic alkaloid present in the seeds ofArgemone mexicana. Experientia 1985 41 1 77 78 10.1007/BF02005884 3967743
    [Google Scholar]
  121. Sood N.N. Sachdev M.S. Mohan M. Gupta S.K. Sachdev H.P.S. Epidemic dropsy following transcutaneous absorption of Argemone mexicana oil. Trans. R. Soc. Trop. Med. Hyg. 1985 79 4 510 512 10.1016/0035‑9203(85)90079‑3 4082260
    [Google Scholar]
  122. Deroussent A. Ré M. Hoellinger H. Cresteil T. Metabolism of sanguinarine in human and in rat: Characterization of oxidative metabolites produced by human CYP1A1 and CYP1A2 and rat liver microsomes using liquid chromatography–tandem mass spectrometry. J. Pharm. Biomed. Anal. 2010 52 3 391 397 10.1016/j.jpba.2009.09.014 19804952
    [Google Scholar]
  123. Ansari K.M. Chauhan L.K.S. Dhawan A. Khanna S.K. Das M. Unequivocal evidence of genotoxic potential of argemone oil in mice. Int. J. Cancer 2004 112 5 890 895 10.1002/ijc.20319 15386392
    [Google Scholar]
  124. Upreti K.K. Das M. Kumar A. Singh G.B. Khanna S.K. Biochemical toxicology of argemone oil. IV short-term oral feeding response in rats. Toxicology 1989 58 3 285 298 10.1016/0300‑483X(89)90142‑X 2799830
    [Google Scholar]
  125. Fifield FW Principles and practice of analytical chemistry. Wiley 2000
    [Google Scholar]
  126. Kaur K.K. Allahbadia G. Singh M. Synthesis and functional significance of poly unsaturated fatty acids (PUFA’s) in body. Acta Sci Nutr Heal. 2018 2 4 8
    [Google Scholar]
  127. Saini R.K. Prasad P. Sreedhar R.V. Akhilender Naidu K. Shang X. Keum Y.S. Omega− 3 polyunsaturated fatty acids (PUFAs): Emerging plant and microbial sources, oxidative stability, bioavailability, and health benefits—A review. Antioxidants 2021 10 10 1627 10.3390/antiox10101627 34679761
    [Google Scholar]
  128. Verma S. Phytochemical and pharmacological study on Argemone mexicana Linn (Papaveraceae). Int. J. Pharm. 2017 7 1 90 93
    [Google Scholar]
  129. Muinat A.A. Mbang F.O.N. Lateef B.G. Temionu E.O. Oluyemisi B.A. Antimicrobial studies of the leaf extract of Argemone mexicana and its ointment formulation. W. Afr. J. Pharm. 2015 26 1 33 40
    [Google Scholar]
  130. Febriyenti F. Fitria N. Mohtar N. Umar S. Noviza D. Rineldi S. Honey gel and film for burn wound. Int. J. Drug Deliv. 2014 6
    [Google Scholar]
/content/journals/cdrr/10.2174/0125899775362872250319082142
Loading
Phytochemical and Phytopharmacological Insights into Argemonemexicana: Integrative Approaches in Eastern Indian Region as Folk Medicine
Bentham Science Publishers ; https://doi.org/10.2174/0125899775362872250319082142
/content/journals/cdrr/10.2174/0125899775362872250319082142
/content/journals/cdrr/10.2174/0125899775362872250319082142
Loading

Data & Media loading...


  • Article Type:     Review Article
Keywords: morphological ; pharmacognostical ; eastern indian ; Argemone mexicana ; phytoconstituents ; phytopharmacology

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test