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2000
Volume 21, Issue 6
  • ISSN: 1573-4072
  • E-ISSN: 1875-6646

Abstract

Aging is a natural biological process that occurs due to various factors like unhealthy diet, environmental factors, genetic factors, and lack of moisture. This process leads to the loss of skin elasticity, also known as sagging. It happens due to the gradual decline of collagen type VII (Col-7) and fibril, which slows down the connection between the dermis and epidermis layers, causing the skin to look aged externally. There are several theories of aging, such as the free radical theory, membrane theory, DNA or genetic theory, neuroendocrine theory, telomerase theory, mitochondrial decline theory, and Hayflick limit theory. According to WHO, by 2030, one in six individuals worldwide will be 60 years or older. There are synthetic compounds available in the market for anti-aging purposes, but they pose various side effects. Natural products play an essential role in managing aging, and anti-aging phytoconstituents are mostly found in plant parts like fruits, stems, roots, and other plant sources that have no side effects. This review focuses on various anti-aging agents derived from plants and other natural sources.

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/content/journals/cbc/10.2174/0115734072313321240604104711
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Natural Bioactive Compounds as Anti-aging Agents: Current and Future Perspectives
Curr. Bioact. Compd. 21, E250624231307 (2025); https://doi.org/10.2174/0115734072313321240604104711
/content/journals/cbc/10.2174/0115734072313321240604104711
/content/journals/cbc/10.2174/0115734072313321240604104711
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  • Article Type:     Review Article
Keyword(s): Anti-aging; antioxidant; bioactive compounds; natural compounds; phytoconstituents; Reactive Oxygen Species (ROS)

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