Adolescent Psychiatry - Volume 15, Issue 2, 2025
Volume 15, Issue 2, 2025
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Autism and Suicide: Strategies to Integrate Emerging Evidence in Child and Adolescent Suicide Risk Assessments
Authors: Mayank Gupta, Nihit Gupta and Theodore A. PettiIntroductionThis narrative review considers implications for the increasing prevalence of diagnosed autism spectrum disorder (ASD) in clinical settings. Clinicians and researchers can be guided through an improved understanding of associated factors increasing the risk for suicidality and suicide in individuals manifesting symptoms of ASD and high ASD traits (ASDTs).
MethodsA systematic literature review is supplemented with reverse citations to ensure updated information. By title and abstract, 456 articles were identified. Of those, 50 were used initially, and 15 were later added manually or through reverse citations.
ResultsHigher Suicidal Thoughts and Behaviors (STBs) and suicide rates exist across the age spectrum in individuals with ASD/high ASDTs compared to matched comparison groups from the general population. Associated, poorly understood factors include comorbid psychiatric conditions and suicide risk factors that overlap with ASD symptoms. Increased risk of STB in higher functioning ASD is emphasized. Interpersonal conflict and depression are significant risk factors, as are comorbid borderline personality, bipolar disorder, anxiety, and obsessive-compulsive disorders.
ConclusionMultiple diagnostic challenges are considered that affect appropriate care to address the increasing incidence of STB and suicide in ASD. This overview integrates extant knowledge for case formulation and treatment planning. It provides support for more focused research to improve ASD-related screening instruments and to address the unique features of ASD-related psychopathology. Improved training is needed for clinicians in screening and preventive efforts and to enhance their competence and comfort for addressing and treating STBs in those with ASDTs and ASD.
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Neurobiological and Neuroanatomical Alterations in Autism Spectrum Disorders: How Can Our Knowledge Help Us Manage Them Better?
Authors: Anthony T. Olofinnade, Adejoke Y. Onaolapo and Olakunle J. OnaolapoNeurodevelopmental disorders like Autism Spectrum Disorders (ASDs) are characterized by neurobehavioral deficits that impair activities of daily living. Despite improvements in our understanding of ASDs, the etiology remains puzzling, with suggestions that its etiopathogenesis is due to both genetic and non-genetic factors. Also, advances in research have provided evidence associating ASD with probably non-distinct neurobiological changes. In this narrative review, we explore recent progress in the understanding of how neuroanatomical, neurobiological, and neuropathological processes impact the etiology and pathogenesis of ASDs. The impact of this knowledge on the development of novel markers and therapies would also be evaluated. Strategy: Using information garnered from current and existing literature, we provide a comprehensive update on the relationship between the brain and ASD. Although the mechanisms underlying ASD pathology are diverse and complex, a complete understanding of their interaction is pertinent to developing effective therapies.
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Effect of COVID-19 and Related Lockdown on Young People’s Worries and Emotions in the Israeli Context
Authors: Meenakshi Shukla, Iris Lavi and Jennifer Y.F. LauIntroduction/ObjectiveThe outbreak of COVID-19 has undoubtedly impacted all sections of the population across countries and continents. Here, we describe the additional challenges that Israeli adolescents had to face due to the pandemic and the ensuing lockdown, besides the difficulties posed by socio-political turmoil in Israel. In particular, the current cross-sectional study aimed to explore experiences of the COVID-19 pandemic and the resulting lockdown among Israeli adolescents.
MethodsA sample of 306 Israeli adolescents (mean age 15.32 ± 1.81 years) was assessed on the level of social restrictions experienced, daily routines, and emotional climate (i.e., worries, negative affect, and anhedonia).
ResultsOur results showed that while most participants (95.04%; 51.04% males) did not personally experience the infection, they reported worrying about their studies (43.14%) and about the health of relatives and friends (34.97%). Females reported being more isolated (t (292) =-2.77, p= .01), having higher negative affect (t (292) = -4.198, p= .02), and reported greater impact of the pandemic on their study (t (292) =-2.44, p= .02), finance (t (292) =-3.10, p= .002), and emotions (t (292) =-2.44, p= .02) than males. Both genders did not differ in their levels of anhedonia, which was low (t (292) = 1.27, p= .20).
ConclusionResults underscore the impact of the pandemic on the academic and social lives of youth and the content of their worries. In the special context of Israel, a country that has undergone significant nationwide challenges, these results indicate the resilience of young people alongside elevated levels of worry and negative emotions.
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Impact of Anaemia on Cognitive Impairment and Depression Levels Among Young Adults: A Cross-sectional Study Highlighting Gender Disparities
Authors: Vinitha Chandrasekaran, Neena Elsa Varghese, Krishnaveni K and Kameswaran RBackgroundAnaemia is a significant health epidemic affecting all age groups, especially adults. This study aimed to identify the impact of cognitive impairment and depression levels according to potential risk factors among young anaemic adults.
MethodsA cross-sectional study was conducted among 546 adults aged 17-25 years. Haemoglobin levels were measured using Sahli's method. Socio-demographic and risk factor data were collected via a questionnaire. Depression and cognitive impairment levels were assessed using the Patient Depression Questionnaire-9 (PDQ-9) and the Cognitive Assessment Questionnaire (CAQ), respectively. ANOVA and Spearman's correlation were used to explore the relationship between anaemia, cognitive impairment, and depression levels. The mean age of participants was 19.41 years (SD = 1.47). Gender distribution included 204 males (mean age = 19.2 years, SD = 1.4) and 342 females (mean age = 19.5 years, SD = 1.5).
ResultsThe overall prevalence of anaemia was 73.2%, with 29.4% males and 43.7% females. Most anaemic patients (52.3%) had a mild degree of anaemia. Among anaemic patients, 48.25% experienced forgetfulness, 44.25% had distractibility, 25.7% had false triggering, and 16.2% reported no cognitive issues. About 37.2% of anaemic patients fell under minimal depression.
ConclusionThe study concludes that there is a significant impact of anaemia on cognitive impairment and depression levels among young adults. Therefore, raising awareness about anaemia in young adults is crucial to prevent complications later in adulthood and during pregnancy.
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Investigating the Prevalence of Suicidal Risk and Associated Risk Factors Among University Students in Southeastern Iran: A Cross-Sectional Study
BackgroundSuicide is a significant health issue among young people globally. According to available statistics and research, it ranks as the third leading cause of death for individuals aged 15-24 and the second leading cause of death among students.
AimThis study was conducted to investigate the risk of suicide and its related factors among students at Jiroft University of Medical Sciences.
MethodsThe descriptive study of the current analysis is a cross-sectional type that was conducted using a multi-stage sampling method on 128 students at Jiroft University of Medical Sciences in 2022. Data were collected using the Beck Scale for Suicide Ideation (BSSI) and analyzed with statistical tests of analysis of variance, Pearson correlation, and multiple regression analysis in SPSS-24 statistical software.
ResultsThe average age of students was 22.14 ± 2.96 years. Seventeen individuals (13.3%) had a history of suicide attempts. The average suicide risk score was 6.18 ± 5.61, indicating a high risk of suicide among students. The suicide risk score differed between individuals with strong religious beliefs and those with little belief (p=0.025). The average score for suicidal risks was lower in individuals with complete religious beliefs.
ConclusionThe study shows that students are at a high risk of suicide. This highlights the need to prioritize mental health, implement effective suicide prevention strategies, and personalize interventions to reduce the risk of suicide among medical students.
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Association between Internet Game Addiction and Social Anxiety Symptoms among Adolescents in the Kingdom of Saudi Arabia
BackgroundInternet Gaming Addiction (IGA) can have a significant impact on the characteristics of individual gamers and may even be a contributing factor to the development of social anxiety symptoms. This study of adolescent Saudi Arabian Internet gamers examined the influences of Internet gaming time and probable Internet Gaming Disorders (IGDs). It investigated the association between Internet game addiction and social anxiety symptoms among them.
MethodologyThe cross-sectional survey was conducted from March to June of 2023 among adolescents in the Saudi population. Probable IGD was measured by using the DSM-5 checklist, and the Arabic version of the Social Phobia Inventory (SPIN) was used to evaluate social phobia or anxiety.
ResultsA total of 764 participants enrolled in the current study, 52% of whom were females, and 48% were males. 42% belonged to the age group 17-18, and 38% were 15-16. 44.8% of participants have a gaming addiction. There was a significant association between social phobia and gaming addiction (p-value ≤0.05). There was a significant association of social phobia with age and gender (p-value ≤0.05).
ConclusionThe findings imply a significant correlation between IGA and psychological concerns, particularly among male adolescents. Excessive internet gaming use leads to higher levels of social anxiety.
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