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2000
Volume 15, Issue 2
  • ISSN: 2210-6766
  • E-ISSN: 2210-6774

Abstract

Introduction

This narrative review considers implications for the increasing prevalence of diagnosed autism spectrum disorder (ASD) in clinical settings. Clinicians and researchers can be guided through an improved understanding of associated factors increasing the risk for suicidality and suicide in individuals manifesting symptoms of ASD and high ASD traits (ASDTs).

Methods

A systematic literature review is supplemented with reverse citations to ensure updated information. By title and abstract, 456 articles were identified. Of those, 50 were used initially, and 15 were later added manually or through reverse citations.

Results

Higher Suicidal Thoughts and Behaviors (STBs) and suicide rates exist across the age spectrum in individuals with ASD/high ASDTs compared to matched comparison groups from the general population. Associated, poorly understood factors include comorbid psychiatric conditions and suicide risk factors that overlap with ASD symptoms. Increased risk of STB in higher functioning ASD is emphasized. Interpersonal conflict and depression are significant risk factors, as are comorbid borderline personality, bipolar disorder, anxiety, and obsessive-compulsive disorders.

Conclusion

Multiple diagnostic challenges are considered that affect appropriate care to address the increasing incidence of STB and suicide in ASD. This overview integrates extant knowledge for case formulation and treatment planning. It provides support for more focused research to improve ASD-related screening instruments and to address the unique features of ASD-related psychopathology. Improved training is needed for clinicians in screening and preventive efforts and to enhance their competence and comfort for addressing and treating STBs in those with ASDTs and ASD.

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2025-09-26

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Autism and Suicide: Strategies to Integrate Emerging Evidence in Child and Adolescent Suicide Risk Assessments
APS 15, 121 (2025); https://doi.org/10.2174/0122106766315899250117115836
/content/journals/aps/10.2174/0122106766315899250117115836
/content/journals/aps/10.2174/0122106766315899250117115836
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  • Article Type:     Review Article
Keyword(s): Autism spectrum disorders; psychopathology; risk factors; screening; suicidal thoughts and behaviors; suicide

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