- ISSN: 2405-5204
- E-ISSN: 2405-5212
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oa Green Procedure for One-Pot Synthesis of Azelaic Acid Derivatives Using Metal Catalysis
- Source: Recent Innovations in Chemical Engineering (Formerly Recent Patents on Chemical Engineering), Volume 11, Issue 3, Dec 2018, p. 185 - 191
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- 01 Dec 2018
Abstract
Background & Objective: A green one-pot synthesis of oleic acid (1) derivatives is promoted by Rare Earth Metal (REM) triflates and commercial Molybdenum dioxo dichloride (MoCl2O2) in the presence hydrogen peroxide as a green oxidant. Results: The protocol permits to govern the oxidation selectivity by simply choosing the proper combination of Mo and Sc catalysts. Conclusion: Methyl oleate epoxide 2a and azelaic acid 6 thus obtained are valuable industrial intermediates for synthesizing bio-compostable plastics, plasticizers of PVC, lubricating oils, cosmetics and pharmaceuticals (bactericides, anti-inflammatories, etc.).
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