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image of Impact of Major Contaminants of Emerging Concern (CECs) on Soil and Associated Health Issues

Abstract

Land directly affects people's health and well-being. Soil is essential for social and economic growth. It is impossible to overstate the urgency of conserving soil, as it is crucial for fostering the development of an ecological civilization and maintaining household stability. A new significant threat to soil health and fertility has emerged in the form of contaminants of emerging concern (CECs). Unlike other pollutants, these CECs (., pharmaceuticals, cosmetics, PFAS, and microplastics) are resistant to microbial degradation; therefore, they persist in soil and can enter the food chain or pollute groundwater supplies. Several researchers worldwide have shown that CECs destroy soil microflora, impair ecological balance, and reduce soil fertility and agricultural productivity. Recent experimental studies have confirmed their presence in cell culture and experimental animal models at concentrations ranging from nanomolar (nM) to millimolar (mM) levels. The unrestricted use of these CECs has resulted in their bioaccumulation at higher levels in the food chain, ultimately reaching human beings. Despite their hazardous nature, no definite environmental laws or FDA regulations exist, adding fuel to the fire. Therefore, we aim to highlight the environmental implications of these CECs and the steps needed to prevent them from transforming into an environmental catastrophe. This review focuses on five key CECs, including nanoparticles, cosmetic additives (phthalates and biphenyls), flame retardants, and microplastics, along with their environmental implications.

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2026-02-10
2026-02-25

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References

  1. Contaminants of emerging concern. 2024. Available from: https://cec-1.itrcweb.org/
  2. K’oreje K.O. Okoth M. Van Langenhove H. Demeestere K. Occurrence and treatment of contaminants of emerging concern in the African aquatic environment: Literature review and a look ahead. J. Environ. Manage. 2020 254 109752 10.1016/j.jenvman.2019.109752 31733478
    [Google Scholar]
  3. Reichert G. Hilgert S. Fuchs S. Azevedo J.C.R. Emerging contaminants and antibiotic resistance in the different environmental matrices of Latin America. Environ. Pollut. 2019 255 Pt 1 113140 10.1016/j.envpol.2019.113140 31541833
    [Google Scholar]
  4. He D. Luo Y. Lu S. Liu M. Song Y. Lei L. Microplastics in soils: Analytical methods, pollution characteristics and ecological risks. Trends Analyt. Chem. 2018 109 163 172 10.1016/j.trac.2018.10.006
    [Google Scholar]
  5. de Souza Machado A.A. Kloas W. Zarfl C. Hempel S. Rillig M.C. Microplastics as an emerging threat to terrestrial ecosystems. Glob. Change Biol. 2018 24 4 1405 1416 10.1111/gcb.14020 29245177
    [Google Scholar]
  6. Nellemann C. Corcoran E. Dead Planet, Living Planet: Biodiversity and Ecosystem Restoration for Sustainable Development: A Rapid Response Assessment. UNEP/Earthprint 2010
    [Google Scholar]
  7. Cheng Z. Hettiarachchi G.M. Kim K.H. Urban soils research: SUITMA 10. J. Environ. Qual. 2021 50 1 2 6 10.1002/jeq2.20191 33368374
    [Google Scholar]
  8. Renner R. The long and the short of perfluorinated replacements. Environ. Sci. Technol. 2006 40 1 12 13 10.1021/es062612a 16433328
    [Google Scholar]
  9. Laitinen J.A. Koponen J. Koikkalainen J. Kiviranta H. Firefighters’ exposure to perfluoroalkyl acids and 2-butoxyethanol present in firefighting foams. Toxicol. Lett. 2014 231 2 227 232 10.1016/j.toxlet.2014.09.007 25447453
    [Google Scholar]
  10. Wang Z. Cousins I.T. Berger U. Hungerbühler K. Scheringer M. Comparative assessment of the environmental hazards of and exposure to perfluoroalkyl phosphonic and phosphinic acids (PFPAs and PFPiAs): Current knowledge, gaps, challenges and research needs. Environ. Int. 2016 89-90 235 247 10.1016/j.envint.2016.01.023 26922149
    [Google Scholar]
  11. Skaar J.S. Ræder E.M. Lyche J.L. Ahrens L. Kallenborn R. Elucidation of contamination sources for poly- and perfluoroalkyl substances (PFASs) on Svalbard (Norwegian Arctic). Environ. Sci. Pollut. Res. Int. 2019 26 8 7356 7363 10.1007/s11356‑018‑2162‑4 29754295
    [Google Scholar]
  12. Houtz E.F. Sutton R. Park J.S. Sedlak M. Poly- and perfluoroalkyl substances in wastewater: Significance of unknown precursors, manufacturing shifts, and likely AFFF impacts. Water Res. 2016 95 142 149 10.1016/j.watres.2016.02.055 26990839
    [Google Scholar]
  13. Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles Toxicological Profile for Perfluoroalkyls. Atlanta, GA Agency for Toxic Substances and Disease Registry 2009
    [Google Scholar]
  14. Fuerhacker M. EU Water Framework Directive and Stockholm Convention: Can we reach the targets for priority substances and persistent organic pollutants? Environ. Sci. Pollut. Res. Int. 2009 16 S1 92 97 10.1007/s11356‑009‑0126‑4 19337768
    [Google Scholar]
  15. Chen S Zhou Y Meng J Wang T Seasonal and annual variations in removal efficiency of perfluoroalkyl substances by different wastewater treatment processes. Environ Pollut 2018 242 Pt B 2059 67 10.1016/j.envpol.2018.06.078 30231460
    [Google Scholar]
  16. Ssebugere P. Sillanpää M. Matovu H. Environmental levels and human body burdens of per- and poly-fluoroalkyl substances in Africa: A critical review. Sci. Total Environ. 2020 739 139913 10.1016/j.scitotenv.2020.139913 32540660
    [Google Scholar]
  17. Strynar M.J. Lindstrom A.B. Nakayama S.F. Egeghy P.P. Helfant L.J. Pilot scale application of a method for the analysis of perfluorinated compounds in surface soils. Chemosphere 2012 86 3 252 257 10.1016/j.chemosphere.2011.09.036 22130124
    [Google Scholar]
  18. Brusseau M.L. Anderson R.H. Guo B. PFAS concentrations in soils: Background levels versus contaminated sites. Sci. Total Environ. 2020 740 140017 10.1016/j.scitotenv.2020.140017 32927568
    [Google Scholar]
  19. Wang W. Rhodes G. Ge J. Yu X. Li H. Uptake and accumulation of per- and polyfluoroalkyl substances in plants. Chemosphere 2020 261 127584 10.1016/j.chemosphere.2020.127584 32717507
    [Google Scholar]
  20. Cai Y. Chen H. Yuan R. Wang F. Chen Z. Zhou B. Toxicity of perfluorinated compounds to soil microbial activity: Effect of carbon chain length, functional group and soil properties. Sci. Total Environ. 2019 690 1162 1169 10.1016/j.scitotenv.2019.06.440 31470479
    [Google Scholar]
  21. O’Carroll D.M. Jeffries T.C. Lee M.J. Developing a roadmap to determine per- and polyfluoroalkyl substances-microbial population interactions. Sci. Total Environ. 2020 712 135994 10.1016/j.scitotenv.2019.135994 31931194
    [Google Scholar]
  22. Pérez F. Nadal M. Navarro-Ortega A. Accumulation of perfluoroalkyl substances in human tissues. Environ. Int. 2013 59 354 362 10.1016/j.envint.2013.06.004 23892228
    [Google Scholar]
  23. Temkin A.M. Hocevar B.A. Andrews D.Q. Naidenko O.V. Kamendulis L.M. Application of the key characteristics of carcinogens to per and polyfluoroalkyl substances. Int. J. Environ. Res. Public Health 2020 17 5 1668 10.3390/ijerph17051668 32143379
    [Google Scholar]
  24. Gilliland F.D. Mandel J.S. Mortality among employees of a perfluorooctanoic acid production plant. J. Occup. Environ. Med. 1993 35 9 950 954 10.1097/00043764‑199309000‑00020 8229349
    [Google Scholar]
  25. Girardi P Merler E. A mortality study on male subjects exposed to polyfluoroalkyl acids with high internal dose of perfluorooctanoic acid.Environ Res 2019 179 Pt A 108743 10.1016/j.envres.2019.108743 31542491
    [Google Scholar]
  26. Darlington R. Barth E. McKernan J. The Challenges of PFAS Remediation. Mil. Eng. 2018 110 712 58 60 29780177
    [Google Scholar]
  27. Maddocks T. Notzon N. PFAS chemicals: 'Shocked and disgusted' Katherine residents demand action on water contamination. 2017. Available from: https://www.abc.net.au/news/2017-10-10/pfas-chemicals-katherine-residents-shocked-demand-action/9034504
  28. Health Canada, Water Talk - Perfluoroalkylated substances in drinking water - Perfluoroalkylated substances (PFAS). 2019. Available from: https://open.canada.ca/data/en/dataset/f2402345-18fe-4d55-ab99-cb89460c6808
  29. Corradini F. Meza P. Eguiluz R. Casado F. Huerta-Lwanga E. Geissen V. Evidence of microplastic accumulation in agricultural soils from sewage sludge disposal. Sci. Total Environ. 2019 671 411 420 10.1016/j.scitotenv.2019.03.368 30933797
    [Google Scholar]
  30. Shruti V.C. Pérez-Guevara F. Roy P.D. Elizalde-Martínez I. Kutralam-Muniasamy G. Identification and characterization of single use oxo/biodegradable plastics from Mexico City, Mexico: Is the advertised labeling useful? Sci. Total Environ. 2020 739 140358 10.1016/j.scitotenv.2020.140358 32758970
    [Google Scholar]
  31. Brizga J. Hubacek K. Feng K. The unintended side effects of bioplastics: Carbon, land, and water footprints. One Earth 2020 3 1 45 53 10.1016/j.oneear.2020.06.016
    [Google Scholar]
  32. Nizzetto L. Futter M. Langaas S. Are agricultural soils dumps for microplastics of urban origin? Environ. Sci. Technol. 2016 50 20 10777 10779 10.1021/acs.est.6b04140 27682621
    [Google Scholar]
  33. Cox K.D. Covernton G.A. Davies H.L. Dower J.F. Juanes F. Dudas S.E. Human consumption of microplastics. Environ. Sci. Technol. 2019 53 12 7068 7074 10.1021/acs.est.9b01517 31184127
    [Google Scholar]
  34. Iqbal S. Xu J. Allen S.D. Unraveling consequences of soil micro- and nano-plastic pollution on soil-plant system: Implications for nitrogen (N) cycling and soil microbial activity. Chemosphere 2020 260 127578 10.1016/j.chemosphere.2020.127578 32683024
    [Google Scholar]
  35. Awet T.T. Kohl Y. Meier F. Effects of polystyrene nanoparticles on the microbiota and functional diversity of enzymes in soil. Environ. Sci. Eur. 2018 30 1 11 10.1186/s12302‑018‑0140‑6 29963347
    [Google Scholar]
  36. McCormick A. Hoellein T.J. Mason S.A. Schluep J. Kelly J.J. Microplastic is an abundant and distinct microbial habitat in an urban river. Environ. Sci. Technol. 2014 48 20 11863 11871 10.1021/es503610r 25230146
    [Google Scholar]
  37. Li C. Gan Y. Dong J. Impact of microplastics on microbial community in sediments of the Huangjinxia Reservoir—water source of a water diversion project in western China. Chemosphere 2020 253 126740 10.1016/j.chemosphere.2020.126740 32304859
    [Google Scholar]
  38. Gionfra S. Plastic pollution in soil. 2024 Available from: https://www.isqaper-is.eu/phocadownload/Briefing_paper_Plastic_pollution_in_soil_v2.pdf
    [Google Scholar]
  39. 2024 Available from: https://www.agribusinessglobal.com/plant-health/npk/microplastics-in-agriculture-challenges for-regulation/#:_:text1/4Microplasticscaninteractwithsoil,sources%2Candalsotheecosystem
  40. Cai Q.Y. Mo C.H. Wu Q.T. Katsoyiannis A. Zeng Q.Y. The status of soil contamination by semivolatile organic chemicals (SVOCs) in China: A review. Sci. Total Environ. 2008 389 2-3 209 224 10.1016/j.scitotenv.2007.08.026 17936334
    [Google Scholar]
  41. Gimeno P. Thomas S. Bousquet C. Identification and quantification of 14 phthalates and 5 non-phthalate plasticizers in PVC medical devices by GC–MS. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2014 949-950 99 108 10.1016/j.jchromb.2013.12.037 24480330
    [Google Scholar]
  42. Wang Y. Zhu H. Kannan K. A review of biomonitoring of phthalate exposures. Toxics 2019 7 2 21 10.3390/toxics7020021 30959800
    [Google Scholar]
  43. Li Y. Huang G. Gu H. Assessing the risk of phthalate ester (PAE) contamination in soils and crops irrigated with treated sewage effluent. Water 2018 10 8 999 10.3390/w10080999
    [Google Scholar]
  44. Niu L. Xu Y. Xu C. Yun L. Liu W. Status of phthalate esters contamination in agricultural soils across China and associated health risks. Environ. Pollut. 2014 195 16 23 10.1016/j.envpol.2014.08.014 25194267
    [Google Scholar]
  45. Zhang X. Li F. Liu T. The influence of polychlorinated biphenyls contamination on soil protein expression. Int. Sch. Res. Notices 2013 2013 126391 10.1155/2013/126391
    [Google Scholar]
  46. Jing R. Fusi S. Kjellerup B.V. Remediation of polychlorinated biphenyls (PCBs) in contaminated soils and sediment: State of knowledge and perspectives. Front. Environ. Sci. 2018 6 79 10.3389/fenvs.2018.00079
    [Google Scholar]
  47. Ye H. Ha M. Yang M. Yue P. Xie Z. Liu C. Di2-ethylhexyl phthalate disrupts thyroid hormone homeostasis through activating the Ras/Akt/TRHr pathway and inducing hepatic enzymes. Sci. Rep. 2017 7 1 40153 10.1038/srep40153 28065941
    [Google Scholar]
  48. Miao H. Liu X. Li J. Associations of urinary phthalate metabolites with risk of papillary thyroid cancer. Chemosphere 2020 241 125093 10.1016/j.chemosphere.2019.125093 31629241
    [Google Scholar]
  49. Marotta V. Russo G. Gambardella C. Human exposure to bisphenol AF and diethylhexylphthalate increases susceptibility to develop differentiated thyroid cancer in patients with thyroid nodules. Chemosphere 2019 218 885 894 10.1016/j.chemosphere.2018.11.084 30609493
    [Google Scholar]
  50. Exposure assessment tools by chemical classes - Other organics. 2020. Available from: https://www.epa.gov/expobox/exposure-assessment-tools-chemical-classes-other-organics
  51. Tan W. Zhang Y. He X. Distribution patterns of phthalic acid esters in soil particle-size fractions determine biouptake in soil-cereal crop systems. Sci. Rep. 2016 6 1 31987 10.1038/srep31987 27555553
    [Google Scholar]
  52. Maddela N.R. Venkateswarlu K. Kakarla D. Megharaj M. Major contaminants of emerging concern in soils: A perspective on potential health risks. Environ. Pollut. 2020 266 115240 10.1016/j.envpol.2020.115240 32698055
    [Google Scholar]
  53. Xu J. Qian W. Li J. Zhang X. He J. Kong D. Polybrominated diphenyl ethers (PBDEs) in soil and dust from plastic production and surrounding areas in eastern of China. Environ. Geochem. Health 2019 41 5 2315 2327 10.1007/s10653‑019‑00247‑0 30689095
    [Google Scholar]
  54. Cai K. Song Q. Yuan W. Human exposure to PBDEs in e-waste areas: A review. Environ. Pollut. 2020 267 115634 10.1016/j.envpol.2020.115634 33254638
    [Google Scholar]
  55. Wang Y Li Z Tan F Xu Y Zhao H Chen J Occurrence and airsoil exchange of organophosphate flame retardants in the air and soil of Dalian, China. Environ Pollut 2020 265 Pt A 114850 10.1016/j.envpol.2020.114850 32474341
    [Google Scholar]
  56. Zhang Y. Guo G.L. Han X. Do polybrominated diphenyl ethers (PBDE) increase the risk of thyroid cancer? Biosci. Hypotheses 2008 1 4 195 199 10.1016/j.bihy.2008.06.003 19122824
    [Google Scholar]
  57. Liu S. Zhao G. Li J. Association of polybrominated diphenylethers (PBDEs) and hydroxylated metabolites (OH-PBDEs) serum levels with thyroid function in thyroid cancer patients. Environ. Res. 2017 159 1 8 10.1016/j.envres.2017.07.042 28759783
    [Google Scholar]
  58. Man Y.B. Lopez B.N. Wang H.S. Leung A.O.W. Chow K.L. Wong M.H. Cancer risk assessment of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in former agricultural soils of Hong Kong. J. Hazard. Mater. 2011 195 92 99 10.1016/j.jhazmat.2011.08.010 21871716
    [Google Scholar]
  59. Hurley S. Goldberg D. Park J.S. A breast cancer case-control study of polybrominated diphenyl ether (PBDE) serum levels among California women. Environ. Int. 2019 127 412 419 10.1016/j.envint.2019.03.043 30954728
    [Google Scholar]
  60. Final scope of the risk evaluation for tris(2-chloroethyl) phosphate. 2020. Available from: https://www.epa.gov/sites/default/files/2020-09/documents/casrn_115-96-8_tris2-chloroethyl_phosphate_tcep_final_scope.pdf
  61. Nafisi S. Maibach H.I. Cosmetic Science and Technology: Theoretical Principles and Applications. Elsevier 2017 337 10.1016/B978‑0‑12‑802005‑0.00022‑7
    [Google Scholar]
  62. Khan I. Saeed K. Khan I. Nanoparticles: Properties, applications and toxicities. Arab. J. Chem. 2019 12 7 908 931 10.1016/j.arabjc.2017.05.011
    [Google Scholar]
  63. Simonin M. Richaume A. Impact of engineered nanoparticles on the activity, abundance, and diversity of soil microbial communities: A review. Environ. Sci. Pollut. Res. Int. 2015 22 18 13710 13723 10.1007/s11356‑015‑4171‑x 25647498
    [Google Scholar]
  64. Loureiro S. Tourinho P.S. Cornelis G. Van Den Brink N.W. D’ıez-Ortiz M. V’azquez-Campos S. Nanomaterials as soil pollutants. Soil Pollution. Canada Academic Press 2018 161 190 10.1016/B978‑0‑12‑849873‑6.00007‑8
    [Google Scholar]
  65. Nanotechnology Risk to Soil Health. 2014. Available from: https://www.iatp.org/sites/default/files/2014_02_19_Biosolids_Nanomaterials_SS_0.pdf
  66. Mazarji M. Minkina T. Sushkova S. Effect of nanomaterials on remediation of polycyclic aromatic hydrocarbons-contaminated soils: A review. J. Environ. Manage. 2021 284 112023 10.1016/j.jenvman.2021.112023 33540196
    [Google Scholar]
  67. Science for environment policy. 2016. Available from: https://environment.ec.europa.eu/research-and-innovation/science-environment-policy_en
  68. 2024 Available from:https://www.ecomundo.eu/en/blog/nanomaterials-endocrine-disruptors
  69. Ecomundo. 2024. Available from: https://ecomundo.eu/en
  70. Javed Z. Dashora K. Mishra M. Fasake V.D. Srivastva A. Effect of accumulation of nanoparticles in soil health-a concern on future. Front Nanosci Nanotechnol 2019 5 1 9 10.15761/FNN.1000181
    [Google Scholar]
  71. Fayiga A.O. Saha U.K. Nanoparticles in biosolids: Effect on soil health and crop growth. Ann Environ Sci Toxicol 2018 2 1 59 67 10.17352/aest.000013
    [Google Scholar]
  72. Pérez-Hernández H. Fernández-Luqueño F. Huerta-Lwanga E. Mendoza-Vega J. Álvarez-Solís José D. Effect of engineered nanoparticles on soil biota: Do they improve the soil quality and crop production or jeopardize them? Land Degrad. Dev. 2020 31 16 2213 2230 10.1002/ldr.3595
    [Google Scholar]
  73. Bai C. Tang M. Toxicological study of metal and metal oxide nanoparticles in zebrafish. J. Appl. Toxicol. 2020 40 1 37 63 10.1002/jat.3910 31884684
    [Google Scholar]
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Impact of Major Contaminants of Emerging Concern (CECs) on Soil and Associated Health Issues
Bentham Science Publishers ; https://doi.org/10.2174/012772574X394831251126101042
/content/journals/rafna/10.2174/012772574X394831251126101042
/content/journals/rafna/10.2174/012772574X394831251126101042
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  • Article Type:     Review Article
Keywords: bioaccumulation ; biphenyls ; Contaminants of emerging concern (CECs) ; flame retardants ; phthalates ; microplastics

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