Probiotics as Immunotherapeutic Adjuvants: Enhancing Viral Defense Against Emerging Pathogens, including Monkeypox

References

1. MazziottaC. TognonM. MartiniF. TorreggianiE. RotondoJ.C. Probiotics mechanism of action on immune cells and beneficial effects on human health.Cells202312118410.3390/cells12010184 36611977
   [Google Scholar]
2. AmroucheT. ChikindasM.L. Probiotics for immunomodulation in prevention against respiratory viral infections with special emphasis on COVID-19.AIMS Microbiol.20228333835610.3934/microbiol.2022024 36317003
   [Google Scholar]
3. KangH.J. ImS.H. Probiotics as an immune modulator.J. Nutr. Sci. Vitaminol.201561S103S10510.3177/jnsv.61.S103 26598815
   [Google Scholar]
4. WangY. MoonA. HuangJ. SunY. QiuH.J. Antiviral effects and underlying mechanisms of probiotics as promising antivirals.Front. Cell. Infect. Microbiol.20221292805010.3389/fcimb.2022.928050 35734576
   [Google Scholar]
5. Di SabatinoA. SantacroceG. RossiC.M. BroglioG. LentiM.V. Role of mucosal immunity and epithelial–vascular barrier in modulating gut homeostasis.Intern. Emerg. Med.20231861635164610.1007/s11739‑023‑03329‑1 37402104
   [Google Scholar]
6. RousseauxA. BrosseauC. BodinierM. Immunomodulation of B lymphocytes by prebiotics, probiotics and synbiotics: application in pathologies.Nutrients202315226910.3390/nu15020269 36678140
   [Google Scholar]
7. VitettaL. SaltzmanE. ThomsenM. NikovT. HallS. Adjuvant probiotics and the intestinal microbiome: Enhancing vaccines and immunotherapy outcomes.Vaccines2017545010.3390/vaccines5040050 29232932
   [Google Scholar]
8. GuoL. SongR. ZhangQ. Profiling of viral load, antibody and inflammatory response of people with monkeypox during hospitalization: A prospective longitudinal cohort study in China.EBioMedicine202410610525410.1016/j.ebiom.2024.105254 39043012
   [Google Scholar]
9. VirkM.S. VirkM.A. HeY. The anti-inflammatory and curative exponent of probiotics: A comprehensive and authentic ingredient for the sustained functioning of major human organs.Nutrients202416454610.3390/nu16040546 38398870
   [Google Scholar]
10. AzadM.A.K. SarkerM. WanD. Immunomodulatory effects of probiotics on cytokine profiles.BioMed Res. Int.20182018111010.1155/2018/8063647 30426014
    [Google Scholar]
11. MahootiM. MiriS.M. AbdolalipourE. GhaemiA. The immunomodulatory effects of probiotics on respiratory viral infections: A hint for COVID-19 treatment?Microb. Pathog.202014810445210.1016/j.micpath.2020.104452 32818576
    [Google Scholar]
12. SinghK. RaoA. Probiotics: A potential immunomodulator in COVID-19 infection management.Nutr. Res.20218711210.1016/j.nutres.2020.12.014 33592454
    [Google Scholar]
13. PetrariuO.A. BarbuI.C. NiculescuA.G. Role of probiotics in managing various human diseases, from oral pathology to cancer and gastrointestinal diseases.Front. Microbiol.202414129644710.3389/fmicb.2023.1296447 38249451
    [Google Scholar]
14. CristoforiF. DargenioV.N. DargenioC. MinielloV.L. BaroneM. FrancavillaR. Anti-inflammatory and immunomodulatory effects of probiotics in gut inflammation: A door to the body.Front. Immunol.20211257838610.3389/fimmu.2021.578386 33717063
    [Google Scholar]
15. TomkinsonS. TriscottC. SchenkE. FoeyA. The potential of probiotics as ingestible adjuvants and immune modulators for antiviral immunity and management of SARS-CoV-2 infection and COVID-19.Pathogens202312792810.3390/pathogens12070928 37513775
    [Google Scholar]
16. KothariD. PatelS. KimS.K. Probiotic supplements might not be universally-effective and safe: A review.Biomed. Pharmacother.201911153754710.1016/j.biopha.2018.12.104 30597307
    [Google Scholar]
17. KazemifardN. DehkohnehA. Baradaran GhavamiS. Probiotics and probiotic-based vaccines: A novel approach for improving vaccine efficacy.Front. Med.2022994045410.3389/fmed.2022.940454 36313997
    [Google Scholar]
18. PerdigonG. AlvarezS. RachidM. AgüeroG. GobbatoN. Immune system stimulation by probiotics.J. Dairy Sci.19957871597160610.3168/jds.S0022‑0302(95)76784‑4 7593855
    [Google Scholar]