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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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Epitope-Paratope Recognition by Knowledge Based Correlation Mapping using Hopfield Network
- Source: Protein and Peptide Letters, Volume 8, Issue 4, Aug 2001, p. 257 - 264
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- 01 Aug 2001
Abstract
The knowledge based correlation mapping (KBCM) is devised here as a unified measure of the information on antigen-antibody complexes available in the Protein Data Banks. This mapping is estimated from a random training sample using a Hopfield Network while representing the epitope and paratope in a complex as 3-dimensional attributed graphs. Identification of paratopes on immunoglobulins against given epitopes is carried out using pattern matching on Hopfield Network with the help of the KBCM.
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