Nucleolin Binds to a cis-Active Region in the Human Desmocollin 2 Promoter

Paresh L. Gadhavi; Steven Howell; Anthony I. Magee; Roger S. Buxton

doi:10.2174/0929866013409247

ISSN: 0929-8665
E-ISSN: 1875-5305

Nucleolin Binds to a cis-Active Region in the Human Desmocollin 2 Promoter
Authors: Paresh L. Gadhavi¹, Steven Howell², Anthony I. Magee³ and Roger S. Buxton⁴
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¹ Division of Membrane Biology1, Division of Protein Structure2, National Institute for Medical Research, Mill Hill, London NW7 1AA, United Kingdom ² Division of Membrane Biology1, Division of Protein Structure2, National Institute for Medical Research, Mill Hill, London NW7 1AA, United Kingdom ³ Division of Membrane Biology1, Division of Protein Structure2, National Institute for Medical Research, Mill Hill, London NW7 1AA, United Kingdom ⁴ Division of Membrane Biology1, Division of Protein Structure2, National Institute for Medical Research, Mill Hill, London NW7 1AA, United Kingdom
Source: Protein and Peptide Letters, Volume 8, Issue 5, Oct 2001, p. 349 - 356
DOI: https://doi.org/10.2174/0929866013409247
- Available online: 01 Oct 2001

Abstract

Affinity chromatography using oligo DNA from a cis-active region (-453 / -389) of the human DSC2 promoter was used to isolate a protein from human CaCo-2 epithelial cells expressing DSC2. The protein was SDS-PAGE purified, trypsinized and analyzed by MALDI-TOF mass spectrometry. Peptide mass fingerprinting identified the protein as nucleolin, a ubiquitously expressed protein involved in gene regulation

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2001-10-01

2025-09-01

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Article Type: Review Article

Keyword(s): DESMOCOLLIN 2 PROMOTER; desmogleins (DSG); desmoplakin (DP); desmosomal cadherins desmocollins (DSC); Glycoproteins; NUCLEOLIN; plakoglobin (PG); plakophilin (PKP)

Nucleolin Binds to a cis-Active Region in the Human Desmocollin 2 Promoter

Abstract

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