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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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The Catalytic Efficiency of Isosteviol Derived Bifunctional Primary Amine-Squaramide on Michael Additions of Acetophenone to Nitroalkenes
- Source: Letters in Organic Chemistry, Volume 19, Issue 8, Aug 2022, p. 677 - 681
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- 01 Aug 2022
Abstract
The isosteviol derived bifunctional primary amine-squaramide organocatalysts were applied in the Michael addition between nitroalkenes and acetophenone. The conjugate addition isomers of two configurations were observed with high yields (up to 93% yield) and good enantioselectivity (up to 91% ee) at room temperature.
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