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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Sulfated Tin Oxide: A Convenient Heterogeneous Catalyst for the Synthesis of 4-Arylmethylidene-3-Substituted-Isoxazol-5(4H)-Ones
- Source: Letters in Organic Chemistry, Volume 18, Issue 12, Dec 2021, p. 945 - 949
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- 01 Dec 2021
Abstract
Synthesis of isoxazole structural heterocyclic compounds is important due to their wide range of biological activities. In the present article, we report a convenient and easy method for the synthesis of 4-arylmethylidene-3-substituted-isoxazol-5(4H)-ones by the one-pot three-component reaction of aldehydes, β-keto ester, and hydroxylamine hydrochloride catalyzed by sulfated tin oxide as a heterogeneous catalyst.
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