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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Diarylmethanols Synthesis by Nickel(II)-catalyzed Addition of Arylboronic Acids to Aryl Aldehydes
- Source: Letters in Organic Chemistry, Volume 17, Issue 4, Apr 2020, p. 248 - 253
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- 01 Apr 2020
Abstract
A practical procedure for the addition of arylboronic acids to aromatic aldehydes has been developed in the presence of NiCl2(PPh3)2/1,3-bis-(2,6-diisopropylphenyl)imidazolium chloride (IPr·HCl) system with good yield. Generally, electron-rich and -neutral aryl aldehydes showed excellent reactivity and provided desired products in high yields. This procedure will provide new way to the synthesis of diarylmethanols.
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