Full text loading...
- ISSN: 1570-1786
- E-ISSN: 1875-6255
-
Trifluoroacetylation of Anilines with Ethyl Trifluoropyruvate Mediated by Copper(I) Chloride
- Source: Letters in Organic Chemistry, Volume 16, Issue 11, Nov 2019, p. 860 - 864
-
- 01 Nov 2019
Abstract
A novel copper(I)-mediated trifluoroacetylation of anilines with ethyl trifluoropyruvate as a trifluoroacetylating reagent has been developed. Although this protocol could provide good yields in most cases, the reaction exhibited the obvious electronic and steric effects of substituents. The trace amount of products was only obtained for the substrates with ortho-substituted or electron-deficient groups.
© Bentham Science Publishers