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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Synthesis of (E)-vinyl Isobutyronitriles via Fe(III)-catalyzed Decarboxylative Cross-coupling of Cinnamic Acids and AIBN under Additive-free Conditions
- Source: Letters in Organic Chemistry, Volume 16, Issue 8, Aug 2019, p. 656 - 661
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- 01 Aug 2019
Abstract
A facile, efficient, additive-free and eco-friendly protocol for the synthesis of (E)-vinyl isobutyronitriles via Fe(III)-catalyzed decarboxylative cross-coupling of cinnamic acids and AIBN (azodiisobutyronitrile) has been developed. The presented methodology offers several advantages such as easy accessibility and stability of substrates, inexpensive catalyst and simple post-treatment procedure.
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