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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Isolation of New Glycosides from Anemarrhena Asphodeloides Rhizome and Screening of their Anticancer Activity
- Source: Letters in Organic Chemistry, Volume 16, Issue 6, Jun 2019, p. 474 - 477
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- 01 Jun 2019
Abstract
In this report, two new steroidal glycosides were isolated and determined from n-butanol fraction of A.asphodeloides. The structures were confirmed in comparison with the spectral data of known compounds by using different spectroscopic analysis approaches including 1D & 2D-NMR techniques and HRMS. The anti-proliferation screening against cancer cell lines A549 and HeLa indicated that compound 1 exhibited good inhibitory activities with IC50 values of 0.79 and 0.55 μg/mL, respectively.
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