Synthesis and Crystal Structure of Calix[4]arene Derivative Containing 1,3-Diketo Moieties

The synthesis of the calix[4]arene derivative containing 1,3-diketo moieties via direct Claisen condensation without protection of the unsubstituted phenolic OH groups is reported. Single crystal X-ray diffraction analysis reveals that the calix unit to be in a cone conformation incorporating two 1,3-diketo subunits disposed in alternate position at the lower rim. And the crystal packing reveals that the overall packing of the complex is staggered anti-parallelly.