Fe3O4 Nanoparticles as Highly Efficient and Recyclable Catalyst for the Synthesis of 4-Hydroxy-3-[aryloyl(benzamido)methyl]coumarin under Solvent-Free Conditions

A clean, efficient and facile one-pot protocol was developed for the synthesis of a series of new 3,4-substituted coumarins (warfarin analogous compounds) by a one-pot reaction using catalytic amount of Fe3O4 nanoparticles under solvent-free conditions. This green method offers significant advantages in terms of its simplicity, low catalyst loadings, high product yields, recyclability of catalyst and non-toxic nature.