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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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N-Methyl-2-Chloropyridinium Iodide/NaNO2/Wet SiO2: Neutral Reagent System for the Nitration of Activated Aromatic Compounds under Very Mild Conditions
- Source: Letters in Organic Chemistry, Volume 12, Issue 2, Feb 2015, p. 136 - 140
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- 01 Feb 2015
Abstract
Mononitration of activated aromatic compounds using N-methyl-2-chloro-pyridinium iodide (Mukaiyama reagent)/ NaNO2/wet SiO2 reagent system under neutral, very mild and environmentally safer reaction condition has been developed. Various structurally diverse aromatic rings are subjected in this condition and the corresponding nitro-aromatic compounds are prepared in moderately high yields.
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