Efficient Copper-catalyzed Cyanation of Aryl Bromides Using 1,3-phenylene- bis-(1H)-tetrazole as an Efficient Ligand

A new method for the synthesis of aryl nitriles has been developed by the cyanation of aryl bromides with K4Fe(CN)6 as a cyanide source in the presence of Cu(OAc)2.H2O as an inexpensive catalyst and a 1,3-phenylene-bis- (1H)-tetrazole ligand. This method has the advantages of high yield, simple methodology and easy work-up.