An Efficient Synthesis of Thiotetrazoles Using Fe3O4 Nanoparticles as a Magnetically Recoverable and Reusable Catalyst

The 5-alkylthio and 5-arylthiotetrazoles were efficiently synthesized from thiocyanates using Fe3O4 nanoparticles as a magnetically recoverable and reusable catalyst. The main advantages allocated to this method are elimination of hydrazoic acid as a dangerous and harmful reagent, high yields and ease of product isolation. The catalyst can be simply recovered by an external magnet and reused with no significant loss in its reactivity.