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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Efficient Synthesis of 2,4,5-Triaryl-1H-Imidazoles from Aromatic Aldehydes with HMDS Catalyzed by N-Bromosaccharin (NBSa)
- Source: Letters in Organic Chemistry, Volume 11, Issue 4, May 2014, p. 287 - 292
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- 01 May 2014
Abstract
A one-pot efficient procedure for the synthesis of 2, 4, 5-triaryl-1H-imidazole derivatives by the reactions of hexamethyldisilazane and arylaldehydes in the presence of N-bromosaccharin (NBSa) is studied. This new method offers several advantages, such as excellent yields, easy workup, short reaction times, and simple procedure.
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