Full text loading...
- ISSN: 1570-1786
- E-ISSN: 1875-6255
-
One-Pot Pseudo Five-Component Green Synthesis of Novel Bis-Betti Bases by the Mannich-Type Reaction
- Source: Letters in Organic Chemistry, Volume 10, Issue 5, Jun 2013, p. 311 - 316
-
- 01 Jun 2013
Abstract
A mild, efficient and straightforward method has been developed for the synthesis of novel bis-Betti bases via a pseudo five-component, one-pot condensation reaction of heteroaryl amines, terephthaldehyde and naphthols under solvent- free conditions. The salient features of this protocol are: simple reaction procedure, shorter reaction time, high to excellent yields, avoidance of aqueous work-up, and column chromatographic separation.
© Bentham Science Publishers