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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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P2O5SiO2 : A Simple and Effective Catalyst for the Synthesis of Nsubstituted 1-Alkyl and 1-Aryl 3-Aminoisoquinolines
- Source: Letters in Organic Chemistry, Volume 10, Issue 4, May 2013, p. 240 - 244
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- 01 May 2013
Abstract
A synthesis of N-substituted 1-alkyl and 1-aryl 3-aminoisoquinolines by cyclocondensation of 2- acylphenylacetonitriles with aliphatic and aromatic amines using P2O5/SiO2 as catalysts is described. Selectivity, simplicity of operation and easy work-up are some advantages of this method.
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