Synthesis and Application of Novel Dithiane Alcohol Ligand Based on Chiral Cyclopropane-backbone for Asymmetric Ethylation of Aromatic Aldehydes

A novel chiral dithiane alcohol ligand, based on chiral cyclopropane-backbone, was easily prepared from (–)- 1R-cis-caronaldehyde. The chiral ligand was used in asymmetric ethylation of aromatic aldehydes to afford the corresponding secondary alcohols with moderate to good enantioselectivity.