An Efficient One-Step Synthesis of 1H-pyrazolo[3,4-b]pyridines in Basic Ionic Liquid [bmim]OH

Chain 1,3-dicarbonyl compounds were firstly used as starting material to react with 5-amino-3-methyl-1- phenylpyrazol and aromatic aldehydes to prepare 1H-pyrazolo[3,4-b]pyridines in basic ionic liquid [bmim]OH. The onestep three-component reaction is simple and efficient. Additionally, water was the only one by-product during the whole process.