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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Expedient and Green Synthesis of Some Novel 4-Thiazolidinones and New 2,4-Disubstituted Thiazoles with Tetrahydro Carbazole Pendant
- Source: Letters in Organic Chemistry, Volume 9, Issue 9, Nov 2012, p. 660 - 663
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- 01 Nov 2012
Abstract
A green and efficient synthesis of novel 4-thiazolidinones 4 from cyclocondensation reaction of 2-(2,3-dihydro- 1H-carbazol-4(9H)-ylidene)hydrazinecarbothioamide 3 and α-haloacids catalyzed by N-methylpyridinium tosylate in quantitative yield is reported. Also, synthesis of new 2,4-disubstituted thiazoles 5 under grinding conditions is reported.
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