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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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An Efficient Green MCR Protocol for the Synthesis of New Betti Bases via Mannich-Type Reaction
- Source: Letters in Organic Chemistry, Volume 9, Issue 6, Jul 2012, p. 451 - 456
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- 01 Jul 2012
Abstract
An efficient solvent and catalyst-free synthesis of new Betti base derivatives via Mannich-type one-pot threecomponent condensation reaction of aminodiazines, salicylaldehyde and naphthols under solvent-free conditions is described. The reactions occur at 80 oC giving high to excellent yields of the products. The work-up procedure is very simple and the products do not require further purification with column chromatography.
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