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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Efficient Synthesis of 3-Aminoimidazo[1,2-a] Pyridines Using Silica-Supported Perchloric Acid (HClO4-SiO2) as a Novel Heterogenous Catalyst
- Source: Letters in Organic Chemistry, Volume 9, Issue 3, Mar 2012, p. 155 - 159
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- 01 Mar 2012
Abstract
One pot three-component reaction of 2-amino pyridines, aldehydes and isocyanides in the presence of silicasupported perchloric acid (HClO4-SiO2), produces 3-aminoimidazo[1,2-a] pyridines in excellent yields. The reaction time is short and work up of reaction is very easy. New compounds were identified by IR, 1H NMR, 13C NMR and Mass spectrum.
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