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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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A Green Method for the Synthesis of 3-Substituted Coumarins Catalyzed by L-Lysine in Water Via Knoevenagel Condensation
- Source: Letters in Organic Chemistry, Volume 9, Issue 1, Jan 2012, p. 19 - 23
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- 01 Jan 2012
Abstract
L-lysine was applied to the synthesis of 3-substituted coumarins through the condensation of various salicylaldehyde with reactive methylene compounds in water. In this work, waste minimization, catalyst recovery, simple operation and easier product work-up were achieved.
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