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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Facile Catalyst-Free Allylation of Isatins Under Mild Conditions in Dimethylformamide
- Source: Letters in Organic Chemistry, Volume 8, Issue 5, Jun 2011, p. 352 - 357
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- 01 Jun 2011
Abstract
The catalyst-free allylation of isatins with allyltrichlorosilane was performed smoothly in DMF under mild conditions and moderate to excellent yields (60%-94%) were obtained. This protocol provided a new and efficient approach for the preparation of 3-allyl-3-hydroxy-2-oxindoles.
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