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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Stereoselective Synthesis of (S,E)-2-(trimethylsilyl)ethyl 3-hydroxy-7- (tritylthio)hept-4-enoate
- Source: Letters in Organic Chemistry, Volume 8, Issue 1, Jan 2011, p. 66 - 69
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- 01 Jan 2011
Abstract
(S,E)-2-(trimethylsilyl)ethyl 3-hydroxy-7-(tritylthio)hept-4-enoate was synthesized from commercially available L-malic acid by the Julia-Kocienski olefination coupling method. This method provides a concise synthetic strategy for (S,E) -3-hydroxy-7-mercaptohept-4-enoic acid.
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