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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Stereoselective Formal Synthesis of (-)-Salicylihalamides A and B Via Prins Cyclisation
- Source: Letters in Organic Chemistry, Volume 7, Issue 6, Sep 2010, p. 457 - 460
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- 01 Sep 2010
Abstract
A stereoselective and convergent formal approach to Salicylihalamide A and B is achieved through our recently developed strategy for the construction of polyketide precursors via Prins cyclisation. The approach mainly relies upon reductive opening of 1-iodomethyl cyclic ethers, Mitsunobu inversion and ring closing metathesis along with Prins cyclisation.
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