One-Pot Three-Component Solvent-Free Syntheses of n-Alkyl-Bridged N,N,N',N'-tetra(2-hydroxybenzyl)diamines and N,N-bis(2-hydroxybenzyl) amines

A simple solvent-free method to prepare four N,N,N',N'-tetra(2-hydroxy-3,5-dimethylbenzyl)diaminoalkanes and four N,N,N',N'-tetra(2-hydroxy-5-t-butyl-3-methylbenzyl)-diaminoalkanes containing a long n-alkyl-bridge (5-8 CH2 groups between N-atoms) is described. In addition, preparations of four dihydrochlorides of prepared n-alkyl-bridged N,N,N',N'-tetra(2-hydroxybenzyl)diamines are described. This method was also tested in the preparation of eight previously reported N,N-bis(2-hydroxybenzyl)amine derivatives.