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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Synthesis of 2,3 and 4,5-Dihydro-hydroxy-isoxazoles and Isoxazoles Under Different pH Conditions
- Source: Letters in Organic Chemistry, Volume 7, Issue 1, Jan 2010, p. 32 - 38
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- 01 Jan 2010
Abstract
Reaction between aryl 1,3-diketoesters 2a-e and hydroxylamine hydrochloride has been investigated under different experimental conditions. Whereas acid conditions gave principally 3,5-isoxazole esters (3a-e), reactions under neutral and basic conditions led to different 4,5 and 2,3-dihydro-hydroxy-isoxazoles 4a-e and 5a-e.
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