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2000
Volume 6, Issue 8
  • ISSN: 1570-1786
  • E-ISSN: 1875-6255

Abstract

An easy solid phase synthesis of oxytocin analogues conjugated to polyaminopolycarboxylic ligand, such as diethylenetriaminepentaacetic acid (DTPA) and tetraazacyclododecanetetraacetic acid (DOTA) is reported. These new products can be labeled with suitable radiometals (e.g. 90Y, 111In, 177Lu), giving rise to radiopharmaceuticals with potential application in imaging and/or therapy of tumors over-expressing oxytocin receptors.

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/content/journals/loc/10.2174/157017809790443023
2009-12-01
2025-08-17
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/content/journals/loc/10.2174/157017809790443023
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  • Article Type:
    Research Article
Keyword(s): DOTA; DTPA; Oxytocin; radiolabeled peptides; solid phase peptide synthesis; targeting
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