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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Solvent-Free Synthesis of 1,3-Diphenyl-5-arylpyrazole Derivatives
- Source: Letters in Organic Chemistry, Volume 6, Issue 5, Jul 2009, p. 384 - 386
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- 01 Jul 2009
Abstract
The synthesis of 1,3-diphenyl-5-arylpyrazoles via the reactions of 2,3-epoxy-1-phenyl-3-aryl-1-propanones with phenylhydrazine was carried out in 48-84% yields at 230 °C under solvent-free condition within 1.5 h. This method provides several advantages such as operational simplicity, higher yield and solvent-free.
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