Full text loading...
- ISSN: 1570-1786
- E-ISSN: 1875-6255
-
Microwave-Promoted Rearrangement of Hecogenin Derivatives into Cnor- D-homo Steroids
- Source: Letters in Organic Chemistry, Volume 6, Issue 2, Mar 2009, p. 126 - 129
-
- 01 Mar 2009
Abstract
By means of microwave irradiation, the rearrangement from 12β-tosylate and 12β-alcohol of hecogenin derivatives into C-nor-D-homo-Δ17a(18)-olefin (2) and the Δ13(17a)-isomer (3) was achieved. With this method, the controlled solvolysis in anhydrous pyridine gave total conversion to desired exocyclic-olefin which is expected to be a building block of isosteroidal alkaloids.
© Bentham Science Publishers