Metal Free One Pot Approach Towards the Synthesis of Hantzsch Esters and their Application as the Hydrogen Source for the Reduction of Activated Olefins Catalysed by Bromo Dimethyl Sulfonium Bromide (BDMS)

An environmentally benign one pot synthesis of dihydropyridines and its use as hydrogen source in the reduction of α,β-unsaturated aldehydes and ketones using catalytic amount of BDMS at room temperature is described. An extensive study on the role of substituents on aldehyde for the formation of Hantzsch esters, reveals that presence of more than one electron donating substituents, hinders the formation of dihydropyridine derivative.