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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Facile and Efficient Synthesis of Ethyl 3-Oxo-5-arylthiopentanoates, the Precursors for Nazarov Reagent
- Source: Letters in Organic Chemistry, Volume 5, Issue 7, Oct 2008, p. 527 - 529
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- 01 Oct 2008
Abstract
A facile, efficient and high-yielding two-step synthesis of 3-oxo-5-arylthiopentanoates - the precursors for Nazarov reagent - from low-cost bench top chemicals like thiophenols, acrylonitrile, zinc and ethyl bromoacetate via the Blaise reaction, is reported.
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