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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Design and Synthesis of Novel Thioether-linked Carbapenem-Oxazolidinone Hybrids as Potential Antimicrobial Agents
- Source: Letters in Organic Chemistry, Volume 5, Issue 5, Jul 2008, p. 336 - 341
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- 01 Jul 2008
Abstract
Discovery of novel antimicrobial agents effective against infections caused by drug-resistant pathogens is an important objective in drug research field. In order to find new structural classes of antibiotics, a series of novel thioetherlinked carbapenem-oxazolidinone hybrids were synthesized. The structures of the hybrids and intermediates were confirmed by 1H NMR, IR, MS and elemental analysis.
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