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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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A Simple and Efficient One-Pot Synthesis of Spirooxindoles in Water Under Microwave Irradiation Conditions
- Source: Letters in Organic Chemistry, Volume 5, Issue 4, Jun 2008, p. 319 - 323
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- 01 Jun 2008
Abstract
A simple and efficient method for the synthesis of spirooxindoles derivatives by one-pot reactions of isatins, activated methylene reagents and activated carbonyl compounds in water under microwave irradiation was reported. This protocol has the advantages of short reaction time, high yields, easy work-up procedure and environmentally benign characters.
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