Bismuth(III) Triflate-Catalyzed Dehydrative Glycosidation Using 1- Hydroxy Sugars

This paper describes the O-glycoside formation from 1-hydroxy sugars by the bismuth(III) triflate-catalyzed dehydrative glycosidation. The reactions of the 1-hydroxy sugars with some primary alcohols in the presence of only 5 mol% bismuth(III) triflate at reflux for 15 min in dichloromethane afforded the O-glycosides in good yields. This paper clarifies several important properties during the bismuth(III) triflate-catalyzed dehydrative glycosidation using 1-hydroxy sugars.